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Safety and Efficacy of Lonapegsomatropin in Children With Growth Hormone Deficiency: enliGHten Trial 2-Year Results.
Maniatis AK, Casella SJ, Nadgir UM, Hofman PL, Saenger P, Chertock ED, Aghajanova EM, Korpal-Szczyrska M, Vlachopapadopoulou E, Malievskiy O, Chaychenko T, Cappa M, Song W, Mao M, Mygind PH, Smith AR, Chessler SD, Komirenko AS, Beckert M, Shu AD, Thornton PS. Maniatis AK, et al. Among authors: mygind ph. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e2680-e2689. doi: 10.1210/clinem/dgac217. J Clin Endocrinol Metab. 2022. PMID: 35428884 Free PMC article. Clinical Trial.
TransCon CNP, a Sustained-Release C-Type Natriuretic Peptide Prodrug, a Potentially Safe and Efficacious New Therapeutic Modality for the Treatment of Comorbidities Associated with Fibroblast Growth Factor Receptor 3-Related Skeletal Dysplasias.
Breinholt VM, Rasmussen CE, Mygind PH, Kjelgaard-Hansen M, Faltinger F, Bernhard A, Zettler J, Hersel U. Breinholt VM, et al. Among authors: mygind ph. J Pharmacol Exp Ther. 2019 Sep;370(3):459-471. doi: 10.1124/jpet.119.258251. Epub 2019 Jun 24. J Pharmacol Exp Ther. 2019. PMID: 31235532
pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Pohl C, Effantin G, Kandiah E, Meier S, Zeng G, Streicher W, Segura DR, Mygind PH, Sandvang D, Nielsen LA, Peters GHJ, Schoehn G, Mueller-Dieckmann C, Noergaard A, Harris P. Pohl C, et al. Among authors: mygind ph. Nat Commun. 2022 Jun 7;13(1):3162. doi: 10.1038/s41467-022-30462-w. Nat Commun. 2022. PMID: 35672293 Free PMC article.
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.
Mygind PH, Fischer RL, Schnorr KM, Hansen MT, Sönksen CP, Ludvigsen S, Raventós D, Buskov S, Christensen B, De Maria L, Taboureau O, Yaver D, Elvig-Jørgensen SG, Sørensen MV, Christensen BE, Kjaerulff S, Frimodt-Moller N, Lehrer RI, Zasloff M, Kristensen HH. Mygind PH, et al. Nature. 2005 Oct 13;437(7061):975-80. doi: 10.1038/nature04051. Nature. 2005. PMID: 16222292
Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.
Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH. Schneider T, et al. Among authors: mygind ph. Science. 2010 May 28;328(5982):1168-72. doi: 10.1126/science.1185723. Science. 2010. PMID: 20508130
Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin.
Jacobsen F, Mohammadi-Tabrisi A, Hirsch T, Mittler D, Mygind PH, Sonksen CP, Raventos D, Kristensen HH, Gatermann S, Lehnhardt M, Daigeler A, Steinau HU, Steinstraesser L. Jacobsen F, et al. Among authors: mygind ph. J Antimicrob Chemother. 2007 Mar;59(3):493-8. doi: 10.1093/jac/dkl513. Epub 2007 Feb 8. J Antimicrob Chemother. 2007. PMID: 17289767
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