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PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
Parhiz H, Shuvaev VV, Pardi N, Khoshnejad M, Kiseleva RY, Brenner JS, Uhler T, Tuyishime S, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: muzykantov vr. J Control Release. 2018 Dec 10;291:106-115. doi: 10.1016/j.jconrel.2018.10.015. Epub 2018 Oct 15. J Control Release. 2018. PMID: 30336167 Free PMC article.
Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs.
Muzykantov VR, Christofidou-Solomidou M, Balyasnikova I, Harshaw DW, Schultz L, Fisher AB, Albelda SM. Muzykantov VR, et al. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2379-84. doi: 10.1073/pnas.96.5.2379. Proc Natl Acad Sci U S A. 1999. PMID: 10051650 Free PMC article.
PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress.
Christofidou-Solomidou M, Scherpereel A, Wiewrodt R, Ng K, Sweitzer T, Arguiri E, Shuvaev V, Solomides CC, Albelda SM, Muzykantov VR. Christofidou-Solomidou M, et al. Among authors: muzykantov vr. Am J Physiol Lung Cell Mol Physiol. 2003 Aug;285(2):L283-92. doi: 10.1152/ajplung.00021.2003. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12851209 Free article.
Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium.
Shuvaev VV, Christofidou-Solomidou M, Scherpereel A, Simone E, Arguiri E, Tliba S, Pick J, Kennel S, Albelda SM, Muzykantov VR. Shuvaev VV, et al. Among authors: muzykantov vr. J Control Release. 2007 Apr 2;118(2):235-44. doi: 10.1016/j.jconrel.2006.12.025. Epub 2007 Jan 8. J Control Release. 2007. PMID: 17270308 Free PMC article.
Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies.
Dziubla TD, Shuvaev VV, Hong NK, Hawkins BJ, Madesh M, Takano H, Simone E, Nakada MT, Fisher A, Albelda SM, Muzykantov VR. Dziubla TD, et al. Among authors: muzykantov vr. Biomaterials. 2008 Jan;29(2):215-27. doi: 10.1016/j.biomaterials.2007.09.023. Epub 2007 Oct 24. Biomaterials. 2008. PMID: 17950837 Free PMC article.
258 results