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A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
Lazo L, Bequet-Romero M, Lemos G, Musacchio A, Cabrales A, Bruno AJ, Ariel Espinosa L, Saloheimo M, Vitikainen M, Hernández A, Emalfarb M, Tchelet R, Suzarte E, Guillén G. Lazo L, et al. Among authors: musacchio a. Vaccine. 2022 Feb 16;40(8):1162-1169. doi: 10.1016/j.vaccine.2022.01.007. Epub 2022 Jan 19. Vaccine. 2022. PMID: 35078661 Free PMC article.
Neutralizing antibodies and broad, functional T cell immune response following immunization with hepatitis C virus proteins-based vaccine formulation.
Martinez-Donato G, Amador-Cañizares Y, Alvarez-Lajonchere L, Guerra I, Pérez A, Dubuisson J, Wychowsk C, Musacchio A, Aguilar D, Dueñas-Carrera S. Martinez-Donato G, et al. Among authors: musacchio a. Vaccine. 2014 Mar 26;32(15):1720-6. doi: 10.1016/j.vaccine.2014.01.046. Epub 2014 Jan 30. Vaccine. 2014. PMID: 24486345
Specific active immunotherapy with a VEGF vaccine in patients with advanced solid tumors. results of the CENTAURO antigen dose escalation phase I clinical trial.
Gavilondo JV, Hernández-Bernal F, Ayala-Ávila M, de la Torre AV, de la Torre J, Morera-Díaz Y, Bequet-Romero M, Sánchez J, Valenzuela CM, Martín Y, Selman-Housein KH, Garabito A, Lazo OC; CENTAURO Group of Investigators. Gavilondo JV, et al. Vaccine. 2014 Apr 17;32(19):2241-50. doi: 10.1016/j.vaccine.2013.11.102. Epub 2014 Feb 11. Vaccine. 2014. PMID: 24530151 Clinical Trial.
Ratio of HCV structural antigens in protein-based vaccine formulations is critical for functional immune response induction.
Martínez-Donato G, Musacchio A, Alvarez-Lajonchere L, Acosta-Rivero N, Amador Y, Guerra I, Peña D, Pérez A, Castro J, Puentes P, Soria Y, Cosme K, Sanchez J, Dueñas-Carrera S. Martínez-Donato G, et al. Among authors: musacchio a. Biotechnol Appl Biochem. 2010 Jul 9;56(3):111-8. doi: 10.1042/BA20090216. Biotechnol Appl Biochem. 2010. PMID: 20515441
Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant.
Acosta-Rivero N, Poutou J, Alvarez-Lajonchere L, Guerra I, Aguilera Y, Musacchio A, Rodríguez A, Aguilar JC, Falcon V, Alvarez-Obregon JC, Soria Y, Torres D, Linares M, Pérez A, Morales-Grillo J, Dueñas-Carrera S. Acosta-Rivero N, et al. Among authors: musacchio a. Biol Res. 2009;42(1):41-56. Epub 2009 Jun 11. Biol Res. 2009. PMID: 19621132 Free article.
251 results