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Page 1
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Among authors: murthy n. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.
Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, Mackley VA, Chang K, Rao A, Skinner C, Shobha T, Mehdipour M, Liu H, Huang WC, Lan F, Bray NL, Li S, Corn JE, Kataoka K, Doudna JA, Conboy I, Murthy N. Lee K, et al. Among authors: murthy n. Nat Biomed Eng. 2017;1:889-901. doi: 10.1038/s41551-017-0137-2. Epub 2017 Oct 2. Nat Biomed Eng. 2017. PMID: 29805845 Free PMC article.
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo.
Park HM, Liu H, Wu J, Chong A, Mackley V, Fellmann C, Rao A, Jiang F, Chu H, Murthy N, Lee K. Park HM, et al. Among authors: murthy n. Nat Commun. 2018 Aug 17;9(1):3313. doi: 10.1038/s41467-018-05641-3. Nat Commun. 2018. PMID: 30120228 Free PMC article.
Making gene editing a therapeutic reality.
Conboy I, Murthy N, Etienne J, Robinson Z. Conboy I, et al. Among authors: murthy n. F1000Res. 2018 Dec 21;7:F1000 Faculty Rev-1970. doi: 10.12688/f1000research.16106.1. eCollection 2018. F1000Res. 2018. PMID: 30613384 Free PMC article. Review.
Non-viral strategies for delivering genome editing enzymes.
Li J, Røise JJ, He M, Das R, Murthy N. Li J, et al. Among authors: murthy n. Adv Drug Deliv Rev. 2021 Jan;168:99-117. doi: 10.1016/j.addr.2020.09.004. Epub 2020 Sep 12. Adv Drug Deliv Rev. 2021. PMID: 32931860 Review.
631 results