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Detection of unamplified target genes via CRISPR-Cas9 immobilized on a graphene field-effect transistor.
Hajian R, Balderston S, Tran T, deBoer T, Etienne J, Sandhu M, Wauford NA, Chung JY, Nokes J, Athaiya M, Paredes J, Peytavi R, Goldsmith B, Murthy N, Conboy IM, Aran K. Hajian R, et al. Among authors: murthy n. Nat Biomed Eng. 2019 Jun;3(6):427-437. doi: 10.1038/s41551-019-0371-x. Epub 2019 Mar 25. Nat Biomed Eng. 2019. PMID: 31097816 Free PMC article.
Making gene editing a therapeutic reality.
Conboy I, Murthy N, Etienne J, Robinson Z. Conboy I, et al. Among authors: murthy n. F1000Res. 2018 Dec 21;7:F1000 Faculty Rev-1970. doi: 10.12688/f1000research.16106.1. eCollection 2018. F1000Res. 2018. PMID: 30613384 Free PMC article. Review.
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.
Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, Mackley VA, Chang K, Rao A, Skinner C, Shobha T, Mehdipour M, Liu H, Huang WC, Lan F, Bray NL, Li S, Corn JE, Kataoka K, Doudna JA, Conboy I, Murthy N. Lee K, et al. Among authors: murthy n. Nat Biomed Eng. 2017;1:889-901. doi: 10.1038/s41551-017-0137-2. Epub 2017 Oct 2. Nat Biomed Eng. 2017. PMID: 29805845 Free PMC article.
An Enzyme-Mediated Amplification Strategy Enables Detection of β-Lactamase Activity Directly in Unprocessed Clinical Samples for Phenotypic Detection of β-Lactam Resistance.
deBoer TR, Tarlton NJ, Yamaji R, Adams-Sapper S, Wu TZ, Maity S, Vesgesna GK, Sadlowski CM, DePaola P 4th, Riley LW, Murthy N. deBoer TR, et al. Among authors: murthy n. Chembiochem. 2018 Oct 18;19(20):2173-2177. doi: 10.1002/cbic.201800443. Epub 2018 Sep 26. Chembiochem. 2018. PMID: 30079487 Free PMC article.
Stimuli-responsive electrodes detect oxidative stress and liver injury.
Aran K, Parades J, Rafi M, Yau JF, Acharya AP, Zibinsky M, Liepmann D, Murthy N. Aran K, et al. Among authors: murthy n. Adv Mater. 2015 Feb 25;27(8):1433-6. doi: 10.1002/adma.201404562. Epub 2014 Dec 23. Adv Mater. 2015. PMID: 25532728 Free PMC article.
631 results