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3,065 results

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Sensitive tumour detection and classification using plasma cell-free DNA methylomes.
Shen SY, Singhania R, Fehringer G, Chakravarthy A, Roehrl MHA, Chadwick D, Zuzarte PC, Borgida A, Wang TT, Li T, Kis O, Zhao Z, Spreafico A, Medina TDS, Wang Y, Roulois D, Ettayebi I, Chen Z, Chow S, Murphy T, Arruda A, O'Kane GM, Liu J, Mansour M, McPherson JD, O'Brien C, Leighl N, Bedard PL, Fleshner N, Liu G, Minden MD, Gallinger S, Goldenberg A, Pugh TJ, Hoffman MM, Bratman SV, Hung RJ, De Carvalho DD. Shen SY, et al. Among authors: murphy t. Nature. 2018 Nov;563(7732):579-583. doi: 10.1038/s41586-018-0703-0. Epub 2018 Nov 14. Nature. 2018. PMID: 30429608 Free article.
Biological and clinical consequences of NPM1 mutations in AML.
Heath EM, Chan SM, Minden MD, Murphy T, Shlush LI, Schimmer AD. Heath EM, et al. Among authors: murphy t. Leukemia. 2017 Apr;31(4):798-807. doi: 10.1038/leu.2017.30. Epub 2017 Jan 23. Leukemia. 2017. PMID: 28111462 Review.
The role of DNA-demethylating agents in cancer therapy.
Mehdipour P, Murphy T, De Carvalho DD. Mehdipour P, et al. Among authors: murphy t. Pharmacol Ther. 2020 Jan;205:107416. doi: 10.1016/j.pharmthera.2019.107416. Epub 2019 Oct 15. Pharmacol Ther. 2020. PMID: 31626871 Review.
Measurable residual disease monitoring provides insufficient lead-time to prevent morphologic relapse in the majority of patients with core-binding factor acute myeloid leukemia.
Puckrin R, Atenafu EG, Claudio JO, Chan S, Gupta V, Maze D, McNamara C, Murphy T, Shuh AC, Yee K, Sibai H, Minden MD, Wei C, Stockley T, Kamel-Reid S, Schimmer AD. Puckrin R, et al. Among authors: murphy t. Haematologica. 2021 Jan 1;106(1):56-63. doi: 10.3324/haematol.2019.235721. Haematologica. 2021. PMID: 31896684 Free PMC article.
Exclusion of persistent mutations in splicing factor genes and isocitrate dehydrogenase 2 improves the prognostic power of molecular measurable residual disease assessment in acute myeloid leukemia.
Murphy T, Zou J, Arruda A, Wang TT, Zhao Z, Zheng Y, Gupta V, Maze D, McNamara C, Minden MD, Schimmer A, Sibai H, Yee K, Capo-Chichi JM, Stockley T, Schuh A, Bratman SV, Chan SM. Murphy T, et al. Haematologica. 2024 Feb 1;109(2):671-675. doi: 10.3324/haematol.2023.283510. Haematologica. 2024. PMID: 37345484 Free PMC article. No abstract available.
Preclinical characterization and clinical trial of CFI-400945, a polo-like kinase 4 inhibitor, in patients with relapsed/refractory acute myeloid leukemia and higher-risk myelodysplastic neoplasms.
Murphy T, Mason JM, Leber B, Bray MR, Chan SM, Gupta V, Khalaf D, Maze D, McNamara CJ, Schimmer AD, Schuh AC, Sibai H, Trus M, Valiquette D, Martin K, Nguyen L, Li X, Mak TW, Minden MD, Yee KWL. Murphy T, et al. Leukemia. 2024 Mar;38(3):502-512. doi: 10.1038/s41375-023-02110-9. Epub 2023 Dec 19. Leukemia. 2024. PMID: 38114624
Anticoagulation prophylaxis reduces venous thromboembolism rate in adult acute lymphoblastic leukaemia treated with asparaginase-based therapy.
Sibai H, Chen R, Liu X, Falcone U, Schimmer A, Schuh A, Law A, McNamara C, Maze D, Yee K, Minden M, Chan SM, Gupta V, Murphy T, Sakurai N, Atenafu EG, Brandwein JM, Seki JT. Sibai H, et al. Among authors: murphy t. Br J Haematol. 2020 Dec;191(5):748-754. doi: 10.1111/bjh.16695. Epub 2020 May 12. Br J Haematol. 2020. PMID: 32395867 Free article. Clinical Trial.
3,065 results