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Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19.
Wong LR, Zheng J, Wilhelmsen K, Li K, Ortiz ME, Schnicker NJ, Thurman A, Pezzulo AA, Szachowicz PJ, Li P, Pan R, Klumpp K, Aswad F, Rebo J, Narumiya S, Murakami M, Zuniga S, Sola I, Enjuanes L, Meyerholz DK, Fortney K, McCray PB Jr, Perlman S. Wong LR, et al. Among authors: murakami m. Nature. 2022 May;605(7908):146-151. doi: 10.1038/s41586-022-04630-3. Epub 2022 Mar 21. Nature. 2022. PMID: 35314834 Free PMC article.
Mast cell maturation is driven via a group III phospholipase A2-prostaglandin D2-DP1 receptor paracrine axis.
Taketomi Y, Ueno N, Kojima T, Sato H, Murase R, Yamamoto K, Tanaka S, Sakanaka M, Nakamura M, Nishito Y, Kawana M, Kambe N, Ikeda K, Taguchi R, Nakamizo S, Kabashima K, Gelb MH, Arita M, Yokomizo T, Nakamura M, Watanabe K, Hirai H, Nakamura M, Okayama Y, Ra C, Aritake K, Urade Y, Morimoto K, Sugimoto Y, Shimizu T, Narumiya S, Hara S, Murakami M. Taketomi Y, et al. Among authors: murakami m. Nat Immunol. 2013 Jun;14(6):554-63. doi: 10.1038/ni.2586. Epub 2013 Apr 28. Nat Immunol. 2013. PMID: 23624557 Free PMC article.
PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.
Hirabayashi T, Anjo T, Kaneko A, Senoo Y, Shibata A, Takama H, Yokoyama K, Nishito Y, Ono T, Taya C, Muramatsu K, Fukami K, Muñoz-Garcia A, Brash AR, Ikeda K, Arita M, Akiyama M, Murakami M. Hirabayashi T, et al. Among authors: murakami m. Nat Commun. 2017 Mar 1;8:14609. doi: 10.1038/ncomms14609. Nat Commun. 2017. PMID: 28248300 Free PMC article.
5,672 results