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Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology.
Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034. doi: 10.1016/j.bmcl.2018.04.063. Epub 2018 Apr 26.
Bioorg Med Chem Lett. 2018.
PMID: 29748051
MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.
Boga SB, Deng Y, Zhu L, Nan Y, Cooper AB, Shipps GW Jr, Doll R, Shih NY, Zhu H, Sun R, Wang T, Paliwal S, Tsui HC, Gao X, Yao X, Desai J, Wang J, Alhassan AB, Kelly J, Patel M, Muppalla K, Gudipati S, Zhang LK, Buevich A, Hesk D, Carr D, Dayananth P, Black S, Mei H, Cox K, Sherborne B, Hruza AW, Xiao L, Jin W, Long B, Liu G, Taylor SA, Kirschmeier P, Windsor WT, Bishop R, Samatar AA.
Boga SB, et al. Among authors: muppalla k.
ACS Med Chem Lett. 2018 Jun 14;9(7):761-767. doi: 10.1021/acsmedchemlett.8b00220. eCollection 2018 Jul 12.
ACS Med Chem Lett. 2018.
PMID: 30034615
Free PMC article.
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Stereoselective addition of 2-phenyloxazol-4-yl trifluoromethanesulfonate to N-sulfinyl imines: application to the synthesis of the HCV protease inhibitor boceprevir.
Morris WJ, Muppalla KK, Cowden C, Ball RG.
Morris WJ, et al. Among authors: muppalla kk.
J Org Chem. 2013 Jan 18;78(2):706-10. doi: 10.1021/jo301856f. Epub 2012 Dec 20.
J Org Chem. 2013.
PMID: 23215022
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Synthesis of resorcin[4]arene cavitands by ring-closing metathesis.
Parulekar SN, Muppalla K, Fronczek FR, Bisht KS.
Parulekar SN, et al. Among authors: muppalla k.
Chem Commun (Camb). 2007 Dec 14;(46):4901-3. doi: 10.1039/b712981e.
Chem Commun (Camb). 2007.
PMID: 18361363
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