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Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug-Resistant Cancer Cells.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Among authors: munirathinam g. ChemMedChem. 2015 Dec;10(12):2014-26. doi: 10.1002/cmdc.201500360. Epub 2015 Oct 5. ChemMedChem. 2015. PMID: 26434977 Free PMC article.
Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary amines.
Dasari R, De Carvalho A, Medellin DC, Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La Chapa JJ, Dybdal-Hargreaves NF, Pillai A, Kälin RE, Mathieu V, Rogelj S, Gonzales CB, Calixto JB, Evidente A, Gautier M, Munirathinam G, Glass R, Burth P, Pelly SC, van Otterlo WA, Kiss R, Kornienko A. Dasari R, et al. Among authors: munirathinam g. Eur J Med Chem. 2015 Oct 20;103:226-37. doi: 10.1016/j.ejmech.2015.08.047. Epub 2015 Aug 29. Eur J Med Chem. 2015. PMID: 26360047 Free PMC article.
Polygodial analog induces apoptosis in LNCaP prostate cancer cells.
Dasari S, Samy ALPA, Narvekar P, Dontaraju VS, Dasari R, Kornienko A, Munirathinam G. Dasari S, et al. Among authors: munirathinam g. Eur J Pharmacol. 2018 Jun 5;828:154-162. doi: 10.1016/j.ejphar.2018.03.029. Epub 2018 Mar 20. Eur J Pharmacol. 2018. PMID: 29572068 Free PMC article.
HMGB1 in hormone-related cancer: a potential therapeutic target.
Srinivasan M, Banerjee S, Palmer A, Zheng G, Chen A, Bosland MC, Kajdacsy-Balla A, Kalyanasundaram R, Munirathinam G. Srinivasan M, et al. Among authors: munirathinam g. Horm Cancer. 2014 Jun;5(3):127-39. doi: 10.1007/s12672-014-0175-0. Epub 2014 Apr 10. Horm Cancer. 2014. PMID: 24718937 Free PMC article. Review.
65 results