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Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus.
Taylor T, Sikorska N, Shchuka VM, Chahar S, Ji C, Macpherson NN, Moorthy SD, de Kort MAC, Mullany S, Khader N, Gillespie ZE, Langroudi L, Tobias IC, Lenstra TL, Mitchell JA, Sexton T. Taylor T, et al. Among authors: mullany s. Genes Dev. 2022 Jun 1;36(11-12):699-717. doi: 10.1101/gad.349489.122. Epub 2022 Jun 16. Genes Dev. 2022. PMID: 35710138 Free PMC article.
Disentangling the genetic overlap and causal relationships between primary open-angle glaucoma, brain morphology and four major neurodegenerative disorders.
Diaz-Torres S, He W, Thorp J, Seddighi S, Mullany S; IGGC International Glaucoma Genetics Consortium; Hammond CJ, Hysi PG, Pasquale LR, Khawaja AP, Hewitt AW, Craig JE, Mackey DA, Wiggs JL, van Duijn C, Lupton MK, Ong JS, MacGregor S, Gharahkhani P. Diaz-Torres S, et al. Among authors: mullany s. EBioMedicine. 2023 Jun;92:104615. doi: 10.1016/j.ebiom.2023.104615. Epub 2023 May 16. EBioMedicine. 2023. PMID: 37201334 Free PMC article.
High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma.
Marshall HN, Mullany S, Han X, Qassim A, He W, Hassall MM, Schmidt J, Thomson D, Nguyen TT, Berry EC, Knight LSW, Hollitt GL, Ridge B, Schulz A, Mills RA, Healey PR, Agar A, Galanopoulos A, Landers J, Graham SL, Hewitt AW, Casson RJ, MacGregor S, Siggs OM, Craig JE. Marshall HN, et al. Among authors: mullany s. Ophthalmology. 2023 Aug;130(8):830-836. doi: 10.1016/j.ophtha.2023.03.028. Epub 2023 Apr 10. Ophthalmology. 2023. PMID: 37044160
No Strong Association between the Apolipoprotein E E4 Allele and Glaucoma: A Multicohort Study.
Mullany S, Diaz-Torres S, Schmidt JM, Thomson D, Qassim A, Marshall HN, Knight LSW, Berry EC, Kolovos A, Dimasi D, Lake S, Mills RA, Landers J, Mitchell P, Healey PR, Commerford T, Klebe S, Souzeau E, Hassall MM, MacGregor S, Gharahkhani P, Siggs OM, Craig JE. Mullany S, et al. Ophthalmol Sci. 2023 Feb 13;3(3):100287. doi: 10.1016/j.xops.2023.100287. eCollection 2023 Sep. Ophthalmol Sci. 2023. PMID: 37007646 Free PMC article.
Physical Activity Is Associated With Macular Thickness: A Multi-Cohort Observational Study.
Berry EC, Marshall HN, Mullany S, Torres SD, Schmidt J, Thomson D, Knight LSW, Hollitt GL, Qassim A, Ridge B, Schulz A, Hassall MM, Nguyen TT, Lake S, Mills RA, Agar A, Galanopoulos A, Landers J, Healey PR, Graham SL, Hewitt AW, MacGregor S, Casson RJ, Siggs OM, Craig JE. Berry EC, et al. Among authors: mullany s. Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):11. doi: 10.1167/iovs.64.3.11. Invest Ophthalmol Vis Sci. 2023. PMID: 36867133 Free PMC article.
Association of High Polygenic Risk With Visual Field Worsening Despite Treatment in Early Primary Open-Angle Glaucoma.
Siggs OM, Qassim A, Han X, Marshall HN, Mullany S, He W, Souzeau E, Galanopoulos A, Agar A, Landers J, Casson RJ, Hewitt AW, Healey PR, Graham SL, MacGregor S, Craig JE. Siggs OM, et al. Among authors: mullany s. JAMA Ophthalmol. 2022 Nov 10;141(1):73-7. doi: 10.1001/jamaophthalmol.2022.4688. Online ahead of print. JAMA Ophthalmol. 2022. PMID: 36355370 Free PMC article.
48 results