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Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells.
Rodenas MC, Peñas-Martínez J, Pardo-Sánchez I, Zaragoza-Huesca D, Ortega-Sabater C, Peña-García J, Espín S, Ricote G, Montenegro S, Ayala-De La Peña F, Luengo-Gil G, Nieto A, García-Molina F, Vicente V, Bernardi F, Lozano ML, Mulero V, Pérez-Sánchez H, Carmona-Bayonas A, Martínez-Martínez I. Rodenas MC, et al. Among authors: mulero v. Front Mol Biosci. 2023 May 19;10:1182925. doi: 10.3389/fmolb.2023.1182925. eCollection 2023. Front Mol Biosci. 2023. PMID: 37275957 Free PMC article.
Suramin, a drug for the treatment of trypanosomiasis, reduces the prothrombotic and metastatic phenotypes of colorectal cancer cells by inhibiting hepsin.
Zaragoza-Huesca D, Rodenas MC, Peñas-Martínez J, Pardo-Sánchez I, Peña-García J, Espín S, Ricote G, Nieto A, García-Molina F, Vicente V, Lozano ML, Carmona-Bayonas A, Mulero V, Pérez-Sánchez H, Martínez-Martínez I. Zaragoza-Huesca D, et al. Among authors: mulero v. Biomed Pharmacother. 2023 Dec;168:115814. doi: 10.1016/j.biopha.2023.115814. Epub 2023 Oct 31. Biomed Pharmacother. 2023. PMID: 37918256 Free article.
A crowdsourcing database for the copy-number variation of the Spanish population.
López-López D, Roldán G, Fernández-Rueda JL, Bostelmann G, Carmona R, Aquino V, Perez-Florido J, Ortuño F, Pita G, Núñez-Torres R, González-Neira A; CSVS Crowdsourcing Group; Peña-Chilet M, Dopazo J. López-López D, et al. Hum Genomics. 2023 Mar 9;17(1):20. doi: 10.1186/s40246-023-00466-8. Hum Genomics. 2023. PMID: 36894999 Free PMC article.
A zebrafish model of Ifih1-driven Aicardi-Goutières syndrome reproduces the interferon signature and the exacerbated inflammation of patients.
Bernal-Bermúdez B, Martínez-López A, Martínez-Morcillo FJ, Tyrkalska SD, Martínez-Menchón T, Mesa-Del-Castillo P, Cayuela ML, Mulero V, García-Moreno D. Bernal-Bermúdez B, et al. Among authors: mulero v. Front Immunol. 2023 Nov 24;14:1294766. doi: 10.3389/fimmu.2023.1294766. eCollection 2023. Front Immunol. 2023. PMID: 38077314 Free PMC article.
ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome.
Rodríguez-Ruiz L, Lozano-Gil JM, Naranjo-Sánchez E, Martínez-Balsalobre E, Martínez-López A, Lachaud C, Blanquer M, Phung TK, García-Moreno D, Cayuela ML, Tyrkalska SD, Pérez-Oliva AB, Mulero V. Rodríguez-Ruiz L, et al. Among authors: mulero v. EMBO Mol Med. 2023 Oct 11;15(10):e18142. doi: 10.15252/emmm.202318142. Epub 2023 Sep 7. EMBO Mol Med. 2023. PMID: 37675820 Free PMC article.
NAMPT and PARylation Are Involved in the Pathogenesis of Atopic Dermatitis.
Arroyo AB, Bernal-Carrión M, Cantón-Sandoval J, Cabas I, Corbalán-Vélez R, Martínez-Menchón T, Ferri B, Cayuela ML, García-Moreno D, Mulero V. Arroyo AB, et al. Among authors: mulero v. Int J Mol Sci. 2023 Apr 28;24(9):7992. doi: 10.3390/ijms24097992. Int J Mol Sci. 2023. PMID: 37175698 Free PMC article.
Evolution of LPS recognition and signaling: The bony fish perspective.
Martínez-López A, Tyrkalska SD, Alcaraz-Pérez F, Cabas I, Candel S, Martínez Morcillo FJ, Sepulcre MP, García-Moreno D, Cayuela ML, Mulero V. Martínez-López A, et al. Among authors: mulero v. Dev Comp Immunol. 2023 Aug;145:104710. doi: 10.1016/j.dci.2023.104710. Epub 2023 Apr 18. Dev Comp Immunol. 2023. PMID: 37080369 Free article. Review.
183 results