Worming pathways to and from DAF-16/FOXO.
Mukhopadhyay A, Oh SW, Tissenbaum HA.
Mukhopadhyay A, et al.
Exp Gerontol. 2006 Oct;41(10):928-34. doi: 10.1016/j.exger.2006.05.020. Epub 2006 Jul 12.
Exp Gerontol. 2006.
PMID: 16839734
Review.
This pathway is comprised of many genes including the insulin/IGF-1 receptor (DAF-2) that signals through a conserved PI 3-kinase/AKT pathway and ultimately down-regulates DAF-16, a forkhead transcription factor (FOXO). ...Signals from the reproductive system regula …
This pathway is comprised of many genes including the insulin/IGF-1 receptor (DAF-2) that signals through a conserved PI 3-kinase/AKT …