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Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases.
Trapecar M, Wogram E, Svoboda D, Communal C, Omer A, Lungjangwa T, Sphabmixay P, Velazquez J, Schneider K, Wright CW, Mildrum S, Hendricks A, Levine S, Muffat J, Lee MJ, Lauffenburger DA, Trumper D, Jaenisch R, Griffith LG. Trapecar M, et al. Among authors: muffat j. Sci Adv. 2021 Jan 29;7(5):eabd1707. doi: 10.1126/sciadv.abd1707. Print 2021 Jan. Sci Adv. 2021. PMID: 33514545 Free PMC article.
Genome-wide CRISPR screen for Zika virus resistance in human neural cells.
Li Y, Muffat J, Omer Javed A, Keys HR, Lungjangwa T, Bosch I, Khan M, Virgilio MC, Gehrke L, Sabatini DM, Jaenisch R. Li Y, et al. Among authors: muffat j. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9527-9532. doi: 10.1073/pnas.1900867116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019072 Free PMC article.
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons.
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, Schüle B, Lippard SJ, Tsai LH, Krainc D, Buchwald SL, Jaenisch R, Lindquist S. Chung CY, et al. Among authors: muffat j. Science. 2013 Nov 22;342(6161):983-7. doi: 10.1126/science.1245296. Epub 2013 Oct 24. Science. 2013. PMID: 24158904 Free PMC article.
Induction of Expansion and Folding in Human Cerebral Organoids.
Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Li Y, et al. Among authors: muffat j. Cell Stem Cell. 2017 Mar 2;20(3):385-396.e3. doi: 10.1016/j.stem.2016.11.017. Epub 2016 Dec 29. Cell Stem Cell. 2017. PMID: 28041895 Free PMC article.
29 results