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Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.
Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH, Levine BL, Wood P, Taran T, Leung M, Mueller KT, Zhang Y, Sen K, Lebwohl D, Pulsipher MA, Grupp SA. Maude SL, et al. Among authors: mueller kt. N Engl J Med. 2018 Feb 1;378(5):439-448. doi: 10.1056/NEJMoa1709866. N Engl J Med. 2018. PMID: 29385370 Free PMC article. Clinical Trial.
Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia.
Mueller KT, Waldron E, Grupp SA, Levine JE, Laetsch TW, Pulsipher MA, Boyer MW, August KJ, Hamilton J, Awasthi R, Stein AM, Sickert D, Chakraborty A, Levine BL, June CH, Tomassian L, Shah SS, Leung M, Taran T, Wood PA, Maude SL. Mueller KT, et al. Clin Cancer Res. 2018 Dec 15;24(24):6175-6184. doi: 10.1158/1078-0432.CCR-18-0758. Epub 2018 Sep 6. Clin Cancer Res. 2018. PMID: 30190371 Free PMC article.
Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.
Stein AM, Grupp SA, Levine JE, Laetsch TW, Pulsipher MA, Boyer MW, August KJ, Levine BL, Tomassian L, Shah S, Leung M, Huang PH, Awasthi R, Mueller KT, Wood PA, June CH. Stein AM, et al. Among authors: mueller kt. CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):285-295. doi: 10.1002/psp4.12388. Epub 2019 Mar 7. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30848084 Free PMC article.
Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction.
Singh N, Lee YG, Shestova O, Ravikumar P, Hayer KE, Hong SJ, Lu XM, Pajarillo R, Agarwal S, Kuramitsu S, Orlando EJ, Mueller KT, Good CR, Berger SL, Shalem O, Weitzman MD, Frey NV, Maude SL, Grupp SA, June CH, Gill S, Ruella M. Singh N, et al. Among authors: mueller kt. Cancer Discov. 2020 Apr;10(4):552-567. doi: 10.1158/2159-8290.CD-19-0813. Epub 2020 Jan 30. Cancer Discov. 2020. PMID: 32001516 Free PMC article.
Tisagenlecleucel cellular kinetics, dose, and immunogenicity in relation to clinical factors in relapsed/refractory DLBCL.
Awasthi R, Pacaud L, Waldron E, Tam CS, Jäger U, Borchmann P, Jaglowski S, Foley SR, van Besien K, Wagner-Johnston ND, Kersten MJ, Schuster SJ, Salles G, Maziarz RT, Anak Ö, Del Corral C, Chu J, Gershgorin I, Pruteanu-Malinici I, Chakraborty A, Mueller KT, Waller EK. Awasthi R, et al. Among authors: mueller kt. Blood Adv. 2020 Feb 11;4(3):560-572. doi: 10.1182/bloodadvances.2019000525. Blood Adv. 2020. PMID: 32045475 Free PMC article. Clinical Trial.
A US perspective on closing the carbon cycle to defossilize difficult-to-electrify segments of our economy.
Shaw WJ, Kidder MK, Bare SR, Delferro M, Morris JR, Toma FM, Senanayake SD, Autrey T, Biddinger EJ, Boettcher S, Bowden ME, Britt PF, Brown RC, Bullock RM, Chen JG, Daniel C, Dorhout PK, Efroymson RA, Gaffney KJ, Gagliardi L, Harper AS, Heldebrant DJ, Luca OR, Lyubovsky M, Male JL, Miller DJ, Prozorov T, Rallo R, Rana R, Rioux RM, Sadow AD, Schaidle JA, Schulte LA, Tarpeh WA, Vlachos DG, Vogt BD, Weber RS, Yang JY, Arenholz E, Helms BA, Huang W, Jordahl JL, Karakaya C, Kian KC, Kothandaraman J, Lercher J, Liu P, Malhotra D, Mueller KT, O'Brien CP, Palomino RM, Qi L, Rodriguez JA, Rousseau R, Russell JC, Sarazen ML, Sholl DS, Smith EA, Stevens MB, Surendranath Y, Tassone CJ, Tran B, Tumas W, Walton KS. Shaw WJ, et al. Among authors: mueller kt. Nat Rev Chem. 2024 May 1. doi: 10.1038/s41570-024-00587-1. Online ahead of print. Nat Rev Chem. 2024. PMID: 38693313 Review.
86 results