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Page 1
Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity.
de Jong SE, van Unen V, Manurung MD, Stam KA, Goeman JJ, Jochems SP, Höllt T, Pezzotti N, Mouwenda YD, Betouke Ongwe ME, Lorenz FR, Kruize YCM, Azimi S, König MH, Vilanova A, Eisemann E, Lelieveldt BPF, Roestenberg M, Sim BKL, Reinders MJT, Fendel R, Hoffman SL, Kremsner PG, Koning F, Mordmüller B, Lell B, Yazdanbakhsh M. de Jong SE, et al. Among authors: mouwenda yd. Nat Immunol. 2021 May;22(5):654-665. doi: 10.1038/s41590-021-00911-7. Epub 2021 Apr 22. Nat Immunol. 2021. PMID: 33888898 Clinical Trial.
Immunological profiles associated with distinct parasitemic states in volunteers undergoing malaria challenge in Gabon.
Manurung MD, de Jong SE, Kruize Y, Mouwenda YD, Ongwe MEB, Honkpehedji YJ, Zinsou JF, Dejon-Agobe JC, Hoffman SL, Kremsner PG, Adegnika AA, Fendel R, Mordmüller B, Roestenberg M, Lell B, Yazdanbakhsh M. Manurung MD, et al. Among authors: mouwenda yd. Sci Rep. 2022 Aug 3;12(1):13303. doi: 10.1038/s41598-022-17725-8. Sci Rep. 2022. PMID: 35922467 Free PMC article.
Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon.
Mouwenda YD, Betouke Ongwe ME, Sonnet F, Stam KA, Labuda LA, De Vries S, Grobusch MP, Zinsou FJ, Honkpehedji YJ, Dejon Agobe JC, Diemert DJ, van Leeuwen R, Bottazzi ME, Hotez PJ, Kremsner PG, Bethony JM, Jochems SP, Adegnika AA, Massinga Loembe M, Yazdanbakhsh M. Mouwenda YD, et al. PLoS Negl Trop Dis. 2021 Oct 1;15(10):e0009732. doi: 10.1371/journal.pntd.0009732. eCollection 2021 Oct. PLoS Negl Trop Dis. 2021. PMID: 34597297 Free PMC article. Clinical Trial.
Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2.
Dejon-Agobe JC, Ateba-Ngoa U, Lalremruata A, Homoet A, Engelhorn J, Nouatin OP, Edoa JR, Fernandes JF, Esen M, Mouwenda YD, Betouke Ongwe EM, Massinga-Loembe M, Hoffman SL, Sim BKL, Theisen M, Kremsner PG, Adegnika AA, Lell B, Mordmüller B. Dejon-Agobe JC, et al. Among authors: mouwenda yd. Clin Infect Dis. 2019 Sep 27;69(8):1377-1384. doi: 10.1093/cid/ciy1087. Clin Infect Dis. 2019. PMID: 30561539 Free PMC article. Clinical Trial.
Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon.
Betouke Ongwe ME, Mouwenda YD, Stam KA, Kremsner PG, Lell B, Diemert D, Bethony J, Bottazzi ME, Hotez PJ, Leeuwen RV, Grobusch MP, Adegnika AA, Mayboroda OA, Yazdanbakhsh M. Betouke Ongwe ME, et al. Among authors: mouwenda yd. PLoS One. 2022 Sep 26;17(9):e0275013. doi: 10.1371/journal.pone.0275013. eCollection 2022. PLoS One. 2022. PMID: 36155987 Free PMC article. Clinical Trial.
Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial.
Adegnika AA, de Vries SG, Zinsou FJ, Honkepehedji YJ, Dejon Agobé JC, Vodonou KG, Bikangui R, Bouyoukou Hounkpatin A, Bache EB, Massinga Loembe M, van Leeuwen R, Molemans M, Kremsner PG, Yazdanbakhsh M, Hotez PJ, Bottazzi ME, Li G, Bethony JM, Diemert DJ, Grobusch MP; HookVac Consortium. Adegnika AA, et al. Lancet Infect Dis. 2021 Feb;21(2):275-285. doi: 10.1016/S1473-3099(20)30288-7. Epub 2020 Sep 11. Lancet Infect Dis. 2021. PMID: 32926834 Clinical Trial.
Immune responses associated with protection induced by chemoattenuated PfSPZ vaccine in malaria-naive Europeans.
Mouwenda YD, Jochems SP, Van Unen V, Betouke Ongwe ME, de Steenhuijsen Piters WA, Stam KA, Massinga Loembe M, Sim BKL, Esen M, Hoffman SL, Kremsner PG, Fendel R, Mordmüller B, Yazdanbakhsh M. Mouwenda YD, et al. JCI Insight. 2024 May 8;9(9):e170210. doi: 10.1172/jci.insight.170210. JCI Insight. 2024. PMID: 38716733 Free article. Clinical Trial.
Urinary Metabolic Profiling in Volunteers Undergoing Malaria Challenge in Gabon.
Betouke Ongwe ME, Kohler I, Manurung MD, Verhoeven A, Derks R, Janse JJ, Mouwenda YD, Kremsner PG, Adegnika AA, Lell B, Everts B, Mayboroda OA, Yazdanbakhsh M. Betouke Ongwe ME, et al. Among authors: mouwenda yd. Metabolites. 2022 Dec 6;12(12):1224. doi: 10.3390/metabo12121224. Metabolites. 2022. PMID: 36557262 Free PMC article.