Mostafa M. Hamed - Search Results

Year	Number of Results
2009	2
2010	2
2011	1
2012	1
2013	2
2014	2
2015	1
2016	4
2017	2
2019	2
2020	2
2021	5
2022	9
2023	1
2024	2

1

Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents.

Khalifa H, Rasheed S, Haupenthal J, Herrmann J, Mandour YM, Abadi AH, Engel M, Müller R, Hirsch AKH, Abdel-Halim M, Hamed MM. Khalifa H, et al. Among authors: hamed mm. Arch Pharm (Weinheim). 2024 Apr;357(4):e2300656. doi: 10.1002/ardp.202300656. Epub 2024 Feb 2. Arch Pharm (Weinheim). 2024. PMID: 38304944

2

Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT.

Exapicheidou IA, Shams A, Ibrahim H, Tsarenko A, Backenköhler M, Hamed MM, Diamanti E, Volkamer A, Slotboom DJ, Hirsch AKH. Exapicheidou IA, et al. Among authors: hamed mm. Chem Commun (Camb). 2024 Jan 18;60(7):870-873. doi: 10.1039/d3cc04738e. Chem Commun (Camb). 2024. PMID: 38164786

3

Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle.

Hamed MM, Abdelsamie AS, Rox K, Schütz C, Kany AM, Röhrig T, Schmelz S, Blankenfeldt W, Arce-Rodriguez A, Borrero-de Acuña JM, Jahn D, Rademacher J, Ringshausen FC, Cramer N, Tümmler B, Hirsch AKH, Hartmann RW, Empting M. Hamed MM, et al. Adv Sci (Weinh). 2023 Feb;10(5):e2204443. doi: 10.1002/advs.202204443. Epub 2023 Jan 3. Adv Sci (Weinh). 2023. PMID: 36596691 Free PMC article.

4

Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors.

Darwish SS, Chen PJ, Hamed MM, Wagdy RA, Chen SH, Abadi AH, Abdel-Halim M, Hwang TL, Engel M. Darwish SS, et al. Among authors: hamed mm. Pharmaceuticals (Basel). 2022 Jun 22;15(7):778. doi: 10.3390/ph15070778. Pharmaceuticals (Basel). 2022. PMID: 35890077 Free PMC article.

5

From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitors.

Wagdy RA, Chen PJ, Hamed MM, Darwish SS, Chen SH, Abadi AH, Abdel-Halim M, Hwang TL, Engel M. Wagdy RA, et al. Among authors: hamed mm. Bioorg Chem. 2022 Oct;127:105977. doi: 10.1016/j.bioorg.2022.105977. Epub 2022 Jun 18. Bioorg Chem. 2022. PMID: 35779404

6

Structure-Guided Optimization of Small-Molecule Folate Uptake Inhibitors Targeting the Energy-Coupling Factor Transporters.

Kiefer AF, Bousis S, Hamed MM, Diamanti E, Haupenthal J, Hirsch AKH. Kiefer AF, et al. Among authors: hamed mm. J Med Chem. 2022 Jul 14;65(13):8869-8880. doi: 10.1021/acs.jmedchem.1c02114. Epub 2022 Jun 16. J Med Chem. 2022. PMID: 35709475 Free PMC article.

7

Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors.

Hamdy J, Emadeldin N, Hamed MM, Frakolaki E, Katsamakas S, Vassilaki N, Zoidis G, Hirsch AKH, Abdel-Halim M, Abadi AH. Hamdy J, et al. Among authors: hamed mm. Pharmaceuticals (Basel). 2022 May 20;15(5):632. doi: 10.3390/ph15050632. Pharmaceuticals (Basel). 2022. PMID: 35631457 Free PMC article.

8

NanoTafla Nanocomposite as a Novel Low-Cost and Eco-Friendly Sorbent for Strontium and Europium Ions.

Abu Elgoud EM, Aly MI, Hamed MM, Nayl AA. Abu Elgoud EM, et al. Among authors: hamed mm. ACS Omega. 2022 Mar 16;7(12):10447-10457. doi: 10.1021/acsomega.1c07255. eCollection 2022 Mar 29. ACS Omega. 2022. PMID: 35382267 Free PMC article.

9

Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Modification of the benzenoid part.

Megahed SH, Rasheed S, Herrmann J, El-Hossary EM, El-Shabrawy YI, Abadi AH, Engel M, Müller R, Abdel-Halim M, Hamed MM. Megahed SH, et al. Among authors: hamed mm. Bioorg Med Chem Lett. 2022 Mar 1;59:128531. doi: 10.1016/j.bmcl.2022.128531. Epub 2022 Jan 7. Bioorg Med Chem Lett. 2022. PMID: 35007723

10

Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier.

Abdallah M, Hamed MM, Frakolaki E, Katsamakas S, Vassilaki N, Bartenschlager R, Zoidis G, Hirsch AKH, Abdel-Halim M, Abadi AH. Abdallah M, et al. Among authors: hamed mm. Eur J Med Chem. 2022 Feb 5;229:114034. doi: 10.1016/j.ejmech.2021.114034. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34959173

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