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Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells.
Board NL, Yuan Z, Wu F, Moskovljevic M, Ravi M, Sengupta S, Mun SS, Simonetti FR, Lai J, Tebas P, Lynn K, Hoh R, Deeks SG, Siliciano JD, Montaner LJ, Siliciano RF. Board NL, et al. Among authors: moskovljevic m. Nat Immunol. 2024 Mar;25(3):462-470. doi: 10.1038/s41590-023-01741-5. Epub 2024 Jan 26. Nat Immunol. 2024. PMID: 38278966 Free PMC article.
The latent reservoir of inducible, infectious HIV-1 does not decrease despite decades of antiretroviral therapy.
McMyn NF, Varriale J, Fray EJ, Zitzmann C, MacLeod H, Lai J, Singhal A, Moskovljevic M, Garcia MA, Lopez BM, Hariharan V, Rhodehouse K, Lynn K, Tebas P, Mounzer K, Montaner LJ, Benko E, Kovacs C, Hoh R, Simonetti FR, Laird GM, Deeks SG, Ribeiro RM, Perelson AS, Siliciano RF, Siliciano JM. McMyn NF, et al. Among authors: moskovljevic m. J Clin Invest. 2023 Sep 1;133(17):e171554. doi: 10.1172/JCI171554. J Clin Invest. 2023. PMID: 37463049 Free PMC article.
Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia.
White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo-Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. White JA, et al. Among authors: moskovljevic m. J Clin Invest. 2023 Mar 15;133(6):e165245. doi: 10.1172/JCI165245. J Clin Invest. 2023. PMID: 36602866 Free PMC article.
TCR-mimic bispecific antibodies to target the HIV-1 reservoir.
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, Jenike K, Ho YC, Gabelli SB, Kinzler KW, Vogelstein B, Zhou S, Siliciano JD, Sadegh-Nasseri S, Reinherz EL, Siliciano RF. Sengupta S, et al. Among authors: moskovljevic m. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2123406119. doi: 10.1073/pnas.2123406119. Epub 2022 Apr 8. Proc Natl Acad Sci U S A. 2022. PMID: 35394875 Free PMC article.
Engaging innate immunity in HIV-1 cure strategies.
Board NL, Moskovljevic M, Wu F, Siliciano RF, Siliciano JD. Board NL, et al. Among authors: moskovljevic m. Nat Rev Immunol. 2022 Aug;22(8):499-512. doi: 10.1038/s41577-021-00649-1. Epub 2021 Nov 25. Nat Rev Immunol. 2022. PMID: 34824401 Review.