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Page 1
Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT. Cohen F, et al. Among authors: moser he. ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5. ChemMedChem. 2019. PMID: 31283109
New aminoglycoside antibiotics.
Dozzo P, Moser HE. Dozzo P, et al. Among authors: moser he. Expert Opin Ther Pat. 2010 Oct;20(10):1321-41. doi: 10.1517/13543776.2010.506189. Expert Opin Ther Pat. 2010. PMID: 20670208 Review.
Synthesis and spectrum of the neoglycoside ACHN-490.
Aggen JB, Armstrong ES, Goldblum AA, Dozzo P, Linsell MS, Gliedt MJ, Hildebrandt DJ, Feeney LA, Kubo A, Matias RD, Lopez S, Gomez M, Wlasichuk KB, Diokno R, Miller GH, Moser HE. Aggen JB, et al. Among authors: moser he. Antimicrob Agents Chemother. 2010 Nov;54(11):4636-42. doi: 10.1128/AAC.00572-10. Epub 2010 Aug 30. Antimicrob Agents Chemother. 2010. PMID: 20805391 Free PMC article.
Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones.
Wagman AS, Cirz R, McEnroe G, Aggen J, Linsell MS, Goldblum AA, Lopez S, Gomez M, Miller G, Simons LJ, Belliotti TR, Harris CR, Poel TJ, Melnick MJ, Gaston RD, Moser HE. Wagman AS, et al. Among authors: moser he. ChemMedChem. 2017 Oct 20;12(20):1687-1692. doi: 10.1002/cmdc.201700426. Epub 2017 Oct 2. ChemMedChem. 2017. PMID: 28881459
Pharmacokinetics in animals and humans of a first-in-class peptide deformylase inhibitor.
Ramanathan-Girish S, McColm J, Clements JM, Taupin P, Barrowcliffe S, Hevizi J, Safrin S, Moore C, Patou G, Moser H, Gadd A, Hoch U, Jiang V, Lofland D, Johnson KW. Ramanathan-Girish S, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4835-42. doi: 10.1128/AAC.48.12.4835-4842.2004. Antimicrob Agents Chemother. 2004. PMID: 15561864 Free PMC article. Clinical Trial.
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q. Reck F, et al. Among authors: moser he. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4. Bioorg Med Chem Lett. 2018. PMID: 29336873
PDF inhibitors: an emerging class of antibacterial drugs.
Johnson KW, Lofland D, Moser HE. Johnson KW, et al. Among authors: moser he. Curr Drug Targets Infect Disord. 2005 Mar;5(1):39-52. doi: 10.2174/1568005053174618. Curr Drug Targets Infect Disord. 2005. PMID: 15777197 Review.
42 results