Moroni F - Search Results

1

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

Berger NA, Besson VC, Boulares AH, Bürkle A, Chiarugi A, Clark RS, Curtin NJ, Cuzzocrea S, Dawson TM, Dawson VL, Haskó G, Liaudet L, Moroni F, Pacher P, Radermacher P, Salzman AL, Snyder SH, Soriano FG, Strosznajder RP, Sümegi B, Swanson RA, Szabo C. Berger NA, et al. Among authors: moroni f. Br J Pharmacol. 2018 Jan;175(2):192-222. doi: 10.1111/bph.13748. Epub 2017 Mar 26. Br J Pharmacol. 2018. PMID: 28213892 Free PMC article. Review.

2

Inhibition of poly(ADP-ribose) glycohydrolase by gallotannin selectively up-regulates expression of proinflammatory genes.

Rapizzi E, Fossati S, Moroni F, Chiarugi A. Rapizzi E, et al. Among authors: moroni f. Mol Pharmacol. 2004 Oct;66(4):890-8. doi: 10.1124/mol.104.000968. Epub 2004 Jun 30. Mol Pharmacol. 2004. PMID: 15229295

3

Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment.

Moroni F, Chiarugi A. Moroni F, et al. FEBS J. 2009 Jan;276(1):36-45. doi: 10.1111/j.1742-4658.2008.06768.x. FEBS J. 2009. PMID: 19087198 Free article.

4

Brain ischemic preconditioning does not require PARP-1.

Faraco G, Blasi F, Min W, Wang ZQ, Moroni F, Chiarugi A. Faraco G, et al. Among authors: moroni f. Stroke. 2010 Jan;41(1):181-3. doi: 10.1161/STROKEAHA.109.567826. Epub 2009 Nov 5. Stroke. 2010. PMID: 19892992

5

Poly(ADP-ribose) polymerase-1 is a nuclear epigenetic regulator of mitochondrial DNA repair and transcription.

Lapucci A, Pittelli M, Rapizzi E, Felici R, Moroni F, Chiarugi A. Lapucci A, et al. Among authors: moroni f. Mol Pharmacol. 2011 Jun;79(6):932-40. doi: 10.1124/mol.110.070110. Epub 2011 Mar 11. Mol Pharmacol. 2011. PMID: 21441600

6

Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo.

Formentini L, Moroni F, Chiarugi A. Formentini L, et al. Among authors: moroni f. Biochem Pharmacol. 2009 May 15;77(10):1612-20. doi: 10.1016/j.bcp.2009.02.017. Epub 2009 Mar 5. Biochem Pharmacol. 2009. PMID: 19426698

7

Mild activation of poly(ADP-ribose) polymerase (PARP) is neuroprotective in rat hippocampal slice models of ischemic tolerance.

Gerace E, Scartabelli T, Formentini L, Landucci E, Moroni F, Chiarugi A, Pellegrini-Giampietro DE. Gerace E, et al. Among authors: moroni f. Eur J Neurosci. 2012 Jul;36(1):1993-2005. doi: 10.1111/j.1460-9568.2012.08116.x. Epub 2012 May 28. Eur J Neurosci. 2012. PMID: 22639866

8

Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia.

Chiarugi A, Meli E, Calvani M, Picca R, Baronti R, Camaioni E, Costantino G, Marinozzi M, Pellegrini-Giampietro DE, Pellicciari R, Moroni F. Chiarugi A, et al. Among authors: moroni f. J Pharmacol Exp Ther. 2003 Jun;305(3):943-9. doi: 10.1124/jpet.103.048934. Epub 2003 Feb 20. J Pharmacol Exp Ther. 2003. PMID: 12606624

9

Poly(ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage.

Meli E, Pangallo M, Baronti R, Chiarugi A, Cozzi A, Pellegrini-Giampietro DE, Moroni F. Meli E, et al. Among authors: moroni f. Toxicol Lett. 2003 Apr 4;139(2-3):153-62. doi: 10.1016/s0378-4274(02)00429-0. Toxicol Lett. 2003. PMID: 12628750

10

Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation.

Fossati S, Cipriani G, Moroni F, Chiarugi A. Fossati S, et al. Among authors: moroni f. Neurochem Int. 2007 Jan;50(1):203-10. doi: 10.1016/j.neuint.2006.08.009. Epub 2006 Oct 18. Neurochem Int. 2007. PMID: 17052800

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