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Identification of a Novel Curcumin Derivative Influencing Notch Pathway and DNA Damage as a Potential Therapeutic Agent in T-ALL.
Zhdanovskaya N, Lazzari S, Caprioglio D, Firrincieli M, Maioli C, Pace E, Imperio D, Talora C, Bellavia D, Checquolo S, Mori M, Screpanti I, Minassi A, Palermo R. Zhdanovskaya N, et al. Among authors: mori m. Cancers (Basel). 2022 Nov 24;14(23):5772. doi: 10.3390/cancers14235772. Cancers (Basel). 2022. PMID: 36497257 Free PMC article.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: mori m. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia.
Quaglio D, Zhdanovskaya N, Tobajas G, Cuartas V, Balducci S, Christodoulou MS, Fabrizi G, Gargantilla M, Priego EM, Carmona Pestaña Á, Passarella D, Screpanti I, Botta B, Palermo R, Mori M, Ghirga F, Pérez-Pérez MJ. Quaglio D, et al. Among authors: mori m. ACS Med Chem Lett. 2019 Feb 26;10(4):639-643. doi: 10.1021/acsmedchemlett.8b00608. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996810 Free PMC article.
A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth.
Lospinoso Severini L, Quaglio D, Basili I, Ghirga F, Bufalieri F, Caimano M, Balducci S, Moretti M, Romeo I, Loricchio E, Maroder M, Botta B, Mori M, Infante P, Di Marcotullio L. Lospinoso Severini L, et al. Among authors: mori m. Cancers (Basel). 2019 Oct 9;11(10):1518. doi: 10.3390/cancers11101518. Cancers (Basel). 2019. PMID: 31601026 Free PMC article.
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Infante P, Faedda R, Bernardi F, Bufalieri F, Lospinoso Severini L, Alfonsi R, Mazzà D, Siler M, Coni S, Po A, Petroni M, Ferretti E, Mori M, De Smaele E, Canettieri G, Capalbo C, Maroder M, Screpanti I, Kool M, Pfister SM, Guardavaccaro D, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: mori m. Nat Commun. 2018 Mar 7;9(1):976. doi: 10.1038/s41467-018-03339-0. Nat Commun. 2018. PMID: 29515120 Free PMC article.
9,797 results