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Ligand binding phenomena that pertain to the metabolic function of renalase.
Beaupre BA, Roman JV, Hoag MR, Meneely KM, Silvaggi NR, Lamb AL, Moran GR. Beaupre BA, et al. Among authors: moran gr. Arch Biochem Biophys. 2016 Dec 15;612:46-56. doi: 10.1016/j.abb.2016.10.011. Epub 2016 Oct 18. Arch Biochem Biophys. 2016. PMID: 27769837 Free PMC article.
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase.
Shen S, Butrin A, Doubleday PF, Melani RD, Beaupre BA, Tavares MT, Ferreira GM, Kelleher NL, Moran GR, Liu D, Silverman RB. Shen S, et al. Among authors: moran gr. J Am Chem Soc. 2021 Jun 16;143(23):8689-8703. doi: 10.1021/jacs.1c02456. Epub 2021 Jun 7. J Am Chem Soc. 2021. PMID: 34097381 Free PMC article.
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase.
Zhu W, Butrin A, Melani RD, Doubleday PF, Ferreira GM, Tavares MT, Habeeb Mohammad TS, Beaupre BA, Kelleher NL, Moran GR, Liu D, Silverman RB. Zhu W, et al. Among authors: moran gr. J Am Chem Soc. 2022 Mar 30;144(12):5629-5642. doi: 10.1021/jacs.2c00924. Epub 2022 Mar 16. J Am Chem Soc. 2022. PMID: 35293728 Free PMC article.
Renalase is an α-NAD(P)H oxidase/anomerase.
Beaupre BA, Carmichael BR, Hoag MR, Shah DD, Moran GR. Beaupre BA, et al. Among authors: moran gr. J Am Chem Soc. 2013 Sep 18;135(37):13980-7. doi: 10.1021/ja407384h. Epub 2013 Sep 5. J Am Chem Soc. 2013. PMID: 23964689
100 results