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Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury.
Jiang W, Welty SE, Couroucli XI, Barrios R, Kondraganti SR, Muthiah K, Yu L, Avery SE, Moorthy B. Jiang W, et al. Among authors: moorthy b. J Pharmacol Exp Ther. 2004 Aug;310(2):512-9. doi: 10.1124/jpet.103.059766. Epub 2004 May 3. J Pharmacol Exp Ther. 2004. PMID: 15123765
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo.
Jiang W, Couroucli XI, Wang L, Barrios R, Moorthy B. Jiang W, et al. Among authors: moorthy b. Biochem Biophys Res Commun. 2011 Apr 1;407(1):79-85. doi: 10.1016/j.bbrc.2011.02.113. Epub 2011 Mar 6. Biochem Biophys Res Commun. 2011. PMID: 21362406 Free PMC article.
180 results