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CAR directs T cell adaptation to bile acids in the small intestine.
Chen ML, Huang X, Wang H, Hegner C, Liu Y, Shang J, Eliason A, Diao H, Park H, Frey B, Wang G, Mosure SA, Solt LA, Kojetin DJ, Rodriguez-Palacios A, Schady DA, Weaver CT, Pipkin ME, Moore DD, Sundrud MS. Chen ML, et al. Among authors: moore dd. Nature. 2021 May;593(7857):147-151. doi: 10.1038/s41586-021-03421-6. Epub 2021 Apr 7. Nature. 2021. PMID: 33828301 Free PMC article.
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.
Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: moore dd. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.
A phospholipid mimetic targeting LRH-1 ameliorates colitis.
Mays SG, D'Agostino EH, Flynn AR, Huang X, Wang G, Liu X, Millings EJ, Okafor CD, Patel A, Cato ML, Cornelison JL, Melchers D, Houtman R, Moore DD, Calvert JW, Jui NT, Ortlund EA. Mays SG, et al. Among authors: moore dd. Cell Chem Biol. 2022 Jul 21;29(7):1174-1186.e7. doi: 10.1016/j.chembiol.2022.03.001. Epub 2022 Mar 21. Cell Chem Biol. 2022. PMID: 35316658 Free article.
Nutrient-sensing nuclear receptors coordinate autophagy.
Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD. Lee JM, et al. Among authors: moore dd. Nature. 2014 Dec 4;516(7529):112-5. doi: 10.1038/nature13961. Epub 2014 Nov 12. Nature. 2014. PMID: 25383539 Free PMC article.
Physiology: A metabolic minuet.
Moore DD. Moore DD. Nature. 2013 Oct 24;502(7472):454-5. doi: 10.1038/502454a. Nature. 2013. PMID: 24153294 No abstract available.
320 results