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Page 1
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial.
Lawrence DS, Muthoga C, Meya DB, Tugume L, Williams D, Rajasingham R, Boulware DR, Mwandumba HC, Moyo M, Dziwani EN, Maheswaran H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Bango F, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Ndhlovu CE, Hlupeni A, Shamu S, Boyer-Chammard T, Molloy SF, Youssouf N, Chen T, Shiri T, Jaffar S, Harrison TS, Jarvis JN, Niessen LW; AMBITION Study Group. Lawrence DS, et al. Among authors: molloy sf. Lancet Glob Health. 2022 Dec;10(12):e1845-e1854. doi: 10.1016/S2214-109X(22)00450-8. Lancet Glob Health. 2022. PMID: 36400090 Free PMC article.
AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial.
Molefi M, Chofle AA, Molloy SF, Kalluvya S, Changalucha JM, Cainelli F, Leeme T, Lekwape N, Goldberg DW, Haverkamp M, Bisson GP, Perfect JR, Letang E, Fenner L, Meintjes G, Burton R, Makadzange T, Ndhlovu CE, Hope W, Harrison TS, Jarvis JN. Molefi M, et al. Among authors: molloy sf. Trials. 2015 Jun 17;16:276. doi: 10.1186/s13063-015-0799-6. Trials. 2015. PMID: 26081985 Free PMC article. Clinical Trial.
Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy.
Williamson PR, Jarvis JN, Panackal AA, Fisher MC, Molloy SF, Loyse A, Harrison TS. Williamson PR, et al. Among authors: molloy sf. Nat Rev Neurol. 2017 Jan;13(1):13-24. doi: 10.1038/nrneurol.2016.167. Epub 2016 Nov 25. Nat Rev Neurol. 2017. PMID: 27886201 Review.
AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.
Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN. Lawrence DS, et al. Among authors: molloy sf. Trials. 2018 Nov 23;19(1):649. doi: 10.1186/s13063-018-3026-4. Trials. 2018. PMID: 30470259 Free PMC article.
Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis.
Shiri T, Loyse A, Mwenge L, Chen T, Lakhi S, Chanda D, Mwaba P, Molloy SF, Heyderman RS, Kanyama C, Hosseinipour MC, Kouanfack C, Temfack E, Mfinanga S, Kivuyo S, Chan AK, Jarvis JN, Lortholary O, Jaffar S, Niessen LW, Harrison TS. Shiri T, et al. Among authors: molloy sf. Clin Infect Dis. 2020 Jan 1;70(1):26-29. doi: 10.1093/cid/ciz163. Clin Infect Dis. 2020. PMID: 30816418 Free PMC article.
Healthcare Costs and Life-years Gained From Treatments Within the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) Trial on Cryptococcal Meningitis: A Comparison of Antifungal Induction Strategies in Sub-Saharan Africa.
Chen T, Mwenge L, Lakhi S, Chanda D, Mwaba P, Molloy SF, Gheorghe A, Griffiths UK, Heyderman RS, Kanyama C, Kouanfack C, Mfinanga S, Chan AK, Temfack E, Kivuyo S, Hosseinipour MC, Lortholary O, Loyse A, Jaffar S, Harrison TS, Niessen LW; ACTA Trial Team. Chen T, et al. Among authors: molloy sf. Clin Infect Dis. 2019 Aug 1;69(4):588-595. doi: 10.1093/cid/ciy971. Clin Infect Dis. 2019. PMID: 30863852 Free PMC article. Clinical Trial.
AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study.
Ponatshego PL, Lawrence DS, Youssouf N, Molloy SF, Alufandika M, Bango F, Boulware DR, Chawinga C, Dziwani E, Gondwe E, Hlupeni A, Hosseinipour MC, Kanyama C, Meya DB, Mosepele M, Muthoga C, Muzoora CK, Mwandumba H, Ndhlovu CE, Rajasingham R, Sayed S, Shamu S, Tsholo K, Tugume L, Williams D, Maheswaran H, Shiri T, Boyer-Chammard T, Loyse A, Chen T, Wang D, Lortholary O, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN, Niessen LW. Ponatshego PL, et al. Among authors: molloy sf. BMJ Open. 2019 Apr 1;9(4):e026288. doi: 10.1136/bmjopen-2018-026288. BMJ Open. 2019. PMID: 30940760 Free PMC article. Clinical Trial.
One-year Mortality Outcomes From the Advancing Cryptococcal Meningitis Treatment for Africa Trial of Cryptococcal Meningitis Treatment in Malawi.
Kanyama C, Molloy SF, Chan AK, Lupiya D, Chawinga C, Adams J, Bright P, Lalloo DG, Heyderman RS, Lortholary O, Jaffar S, Loyse A, van Oosterhout JJ, Hosseinipour MC, Harrison TS. Kanyama C, et al. Among authors: molloy sf. Clin Infect Dis. 2020 Jan 16;70(3):521-524. doi: 10.1093/cid/ciz454. Clin Infect Dis. 2020. PMID: 31155650 Free PMC article. Clinical Trial.
A pragmatic approach to managing antiretroviral therapy-experienced patients diagnosed with HIV-associated cryptococcal meningitis: impact of antiretroviral therapy adherence and duration.
Alufandika M, Lawrence DS, Boyer-Chammard T, Kanyama C, Ndhlovu CE, Mosepele M, Tugume L, Meya D, Boulware DR, Rhein J, Muzoora C, Youssouf N, Molloy SF, Schutz C, Lortholary O, Meintjes G, Mwandumba HC, Harrison TS, Jarvis JN; and the AMBITION-cm Study Group. Alufandika M, et al. Among authors: molloy sf. AIDS. 2020 Jul 15;34(9):1425-1428. doi: 10.1097/QAD.0000000000002556. AIDS. 2020. PMID: 32590438 Free PMC article. No abstract available.
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Comins K, Singh A, Muzoora C, Jjunju S, Nuwagira E, Mosepele M, Leeme T, Siamisang K, Ndhlovu CE, Hlupeni A, Mutata C, van Widenfelt E, Chen T, Wang D, Hope W, Boyer-Chammard T, Loyse A, Molloy SF, Youssouf N, Lortholary O, Lalloo DG, Jaffar S, Harrison TS; Ambition Study Group. Jarvis JN, et al. Among authors: molloy sf. N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904. N Engl J Med. 2022. PMID: 35320642 Free PMC article. Clinical Trial.
48 results