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Proteasome-associated deubiquitinases and cancer.
Cancer Metastasis Rev. 2017 Dec;36(4):635-653. doi: 10.1007/s10555-017-9697-6.
Cancer Metastasis Rev. 2017.
PMID: 29134486
Free PMC article.
Review.
Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation.
Hillert EK, Brnjic S, Zhang X, Mazurkiewicz M, Saei AA, Mofers A, Selvaraju K, Zubarev R, Linder S, D'Arcy P.
Hillert EK, et al. Among authors: mofers a.
Cancer Lett. 2019 Apr 28;448:70-83. doi: 10.1016/j.canlet.2019.02.003. Epub 2019 Feb 13.
Cancer Lett. 2019.
PMID: 30768956
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Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system.
Selvaraju K, Mofers A, Pellegrini P, Salomonsson J, Ahlner A, Morad V, Hillert EK, Espinosa B, Arnér ESJ, Jensen L, Malmström J, Turkina MV, D'Arcy P, Walters MA, Sunnerhagen M, Linder S.
Selvaraju K, et al. Among authors: mofers a.
Sci Rep. 2019 Jul 8;9(1):9841. doi: 10.1038/s41598-019-46168-x.
Sci Rep. 2019.
PMID: 31285509
Free PMC article.
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Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570.
Pellegrini P, Selvaraju K, Faustini E, Mofers A, Zhang X, Ternerot J, Schubert A, Linder S, D Arcy P.
Pellegrini P, et al. Among authors: mofers a.
Int J Mol Sci. 2020 Jul 4;21(13):4757. doi: 10.3390/ijms21134757.
Int J Mol Sci. 2020.
PMID: 32635430
Free PMC article.
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Identification of proteasome inhibitors using analysis of gene expression profiles.
Mofers A, Selvaraju K, Gubat J, D'Arcy P, Linder S.
Mofers A, et al.
Eur J Pharmacol. 2020 Dec 15;889:173709. doi: 10.1016/j.ejphar.2020.173709. Epub 2020 Nov 6.
Eur J Pharmacol. 2020.
PMID: 33166494
Free article.
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Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15.
Mofers A, Perego P, Selvaraju K, Gatti L, Gullbo J, Linder S, D'Arcy P.
Mofers A, et al.
PLoS One. 2019 Oct 22;14(10):e0223807. doi: 10.1371/journal.pone.0223807. eCollection 2019.
PLoS One. 2019.
PMID: 31639138
Free PMC article.
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Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system.
Selvaraju K, Mofers A, Pellegrini P, Salomonsson J, Ahlner A, Morad V, Hillert EK, Espinosa B, Arnér ESJ, Jensen L, Malmström J, Turkina MV, D'Arcy P, Walters MA, Sunnerhagen M, Linder S.
Selvaraju K, et al. Among authors: mofers a.
Sci Rep. 2019 Nov 20;9(1):17501. doi: 10.1038/s41598-019-53667-4.
Sci Rep. 2019.
PMID: 31745183
Free PMC article.
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MYC is downregulated by a mitochondrial checkpoint mechanism.
Zhang X, Mofers A, Hydbring P, Olofsson MH, Guo J, Linder S, D'Arcy P.
Zhang X, et al. Among authors: mofers a.
Oncotarget. 2017 Oct 6;8(52):90225-90237. doi: 10.18632/oncotarget.21653. eCollection 2017 Oct 27.
Oncotarget. 2017.
PMID: 29163823
Free PMC article.
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