Moench T - Search Results

1

Vaginal concentrations of lactic acid potently inactivate HIV.

Aldunate M, Tyssen D, Johnson A, Zakir T, Sonza S, Moench T, Cone R, Tachedjian G. Aldunate M, et al. Among authors: moench t. J Antimicrob Chemother. 2013 Sep;68(9):2015-25. doi: 10.1093/jac/dkt156. Epub 2013 May 8. J Antimicrob Chemother. 2013. PMID: 23657804 Free PMC article.

2

Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid.

Tyssen D, Wang YY, Hayward JA, Agius PA, DeLong K, Aldunate M, Ravel J, Moench TR, Cone RA, Tachedjian G. Tyssen D, et al. mSphere. 2018 Jul 5;3(4):e00055-18. doi: 10.1128/mSphere.00055-18. mSphere. 2018. PMID: 29976641 Free PMC article.

3

In vaginal fluid, bacteria associated with bacterial vaginosis can be suppressed with lactic acid but not hydrogen peroxide.

O'Hanlon DE, Moench TR, Cone RA. O'Hanlon DE, et al. BMC Infect Dis. 2011 Jul 19;11:200. doi: 10.1186/1471-2334-11-200. BMC Infect Dis. 2011. PMID: 21771337 Free PMC article.

4

SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans.

Price CF, Tyssen D, Sonza S, Davie A, Evans S, Lewis GR, Xia S, Spelman T, Hodsman P, Moench TR, Humberstone A, Paull JR, Tachedjian G. Price CF, et al. Among authors: moench tr. PLoS One. 2011;6(9):e24095. doi: 10.1371/journal.pone.0024095. Epub 2011 Sep 15. PLoS One. 2011. PMID: 21935377 Free PMC article. Clinical Trial.

5

Vaginal pH and microbicidal lactic acid when lactobacilli dominate the microbiota.

O'Hanlon DE, Moench TR, Cone RA. O'Hanlon DE, et al. PLoS One. 2013 Nov 6;8(11):e80074. doi: 10.1371/journal.pone.0080074. eCollection 2013. PLoS One. 2013. PMID: 24223212 Free PMC article.

6

Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli.

O'Hanlon DE, Lanier BR, Moench TR, Cone RA. O'Hanlon DE, et al. BMC Infect Dis. 2010 May 19;10:120. doi: 10.1186/1471-2334-10-120. BMC Infect Dis. 2010. PMID: 20482854 Free PMC article.

7

Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source.

Boskey ER, Cone RA, Whaley KJ, Moench TR. Boskey ER, et al. Among authors: moench tr. Hum Reprod. 2001 Sep;16(9):1809-13. doi: 10.1093/humrep/16.9.1809. Hum Reprod. 2001. PMID: 11527880

8

Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification.

Boskey ER, Telsch KM, Whaley KJ, Moench TR, Cone RA. Boskey ER, et al. Among authors: moench tr. Infect Immun. 1999 Oct;67(10):5170-5. doi: 10.1128/IAI.67.10.5170-5175.1999. Infect Immun. 1999. PMID: 10496892 Free PMC article.

9

Human monoclonal antibody stability and activity at vaginal pH.

Castle PE, Karp DA, Zeitlin L, García-Moreno E B, Moench TR, Whaley KJ, Cone RA. Castle PE, et al. J Reprod Immunol. 2002 Jul-Aug;56(1-2):61-76. doi: 10.1016/s0165-0378(02)00013-x. J Reprod Immunol. 2002. PMID: 12106884

10

Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model.

Olmsted SS, Khanna KV, Ng EM, Whitten ST, Johnson ON 3rd, Markham RB, Cone RA, Moench TR. Olmsted SS, et al. Among authors: moench tr. BMC Infect Dis. 2005 Sep 30;5:79. doi: 10.1186/1471-2334-5-79. BMC Infect Dis. 2005. PMID: 16194280 Free PMC article.

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