Moehle K - Search Results

1

Author Correction: Chimeric peptidomimetic antibiotics against Gram-negative bacteria.

Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D. Luther A, et al. Among authors: moehle k. Nature. 2019 Dec;576(7786):E5. doi: 10.1038/s41586-019-1810-2. Nature. 2019. PMID: 31758154

2

A new family of beta-hairpin mimetics based on a trypsin inhibitor from sunflower seeds.

Descours A, Moehle K, Renard A, Robinson JA. Descours A, et al. Among authors: moehle k. Chembiochem. 2002 Apr 2;3(4):318-23. doi: 10.1002/1439-7633(20020402)3:4<318::AID-CBIC318>3.0.CO;2-W. Chembiochem. 2002. PMID: 11933232

3

Macrocyclic hairpin mimetics of the cationic antimicrobial peptide protegrin I: a new family of broad-spectrum antibiotics.

Shankaramma SC, Athanassiou Z, Zerbe O, Moehle K, Mouton C, Bernardini F, Vrijbloed JW, Obrecht D, Robinson JA. Shankaramma SC, et al. Among authors: moehle k. Chembiochem. 2002 Nov 4;3(11):1126-33. doi: 10.1002/1439-7633(20021104)3:11<1126::AID-CBIC1126>3.0.CO;2-I. Chembiochem. 2002. PMID: 12404639

4

A family of macrocyclic antibiotics with a mixed peptide-peptoid beta-hairpin backbone conformation.

Shankaramma SC, Moehle K, James S, Vrijbloed JW, Obrecht D, Robinson JA. Shankaramma SC, et al. Among authors: moehle k. Chem Commun (Camb). 2003 Aug 7;(15):1842-3. doi: 10.1039/b304310j. Chem Commun (Camb). 2003. PMID: 12931994

5

Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.

Fasan R, Dias RL, Moehle K, Zerbe O, Vrijbloed JW, Obrecht D, Robinson JA. Fasan R, et al. Among authors: moehle k. Angew Chem Int Ed Engl. 2004 Apr 13;43(16):2109-12. doi: 10.1002/anie.200353242. Angew Chem Int Ed Engl. 2004. PMID: 15083458 No abstract available.

6

Crystal structure of an NPNA-repeat motif from the circumsporozoite protein of the malaria parasite Plasmodium falciparum.

Ghasparian A, Moehle K, Linden A, Robinson JA. Ghasparian A, et al. Among authors: moehle k. Chem Commun (Camb). 2006 Jan 14;(2):174-6. doi: 10.1039/b510812h. Epub 2005 Nov 21. Chem Commun (Camb). 2006. PMID: 16372096

7

Protein ligand design: from phage display to synthetic protein epitope mimetics in human antibody Fc-binding peptidomimetics.

Dias RL, Fasan R, Moehle K, Renard A, Obrecht D, Robinson JA. Dias RL, et al. Among authors: moehle k. J Am Chem Soc. 2006 Mar 1;128(8):2726-32. doi: 10.1021/ja057513w. J Am Chem Soc. 2006. PMID: 16492060

8

Structure-activity studies in a family of beta-hairpin protein epitope mimetic inhibitors of the p53-HDM2 protein-protein interaction.

Fasan R, Dias RL, Moehle K, Zerbe O, Obrecht D, Mittl PR, Grütter MG, Robinson JA. Fasan R, et al. Among authors: moehle k. Chembiochem. 2006 Mar;7(3):515-26. doi: 10.1002/cbic.200500452. Chembiochem. 2006. PMID: 16511824

9

Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles.

DeMarco SJ, Henze H, Lederer A, Moehle K, Mukherjee R, Romagnoli B, Robinson JA, Brianza F, Gombert FO, Lociuro S, Ludin C, Vrijbloed JW, Zumbrunn J, Obrecht JP, Obrecht D, Brondani V, Hamy F, Klimkait T. DeMarco SJ, et al. Among authors: moehle k. Bioorg Med Chem. 2006 Dec 15;14(24):8396-404. doi: 10.1016/j.bmc.2006.09.003. Epub 2006 Sep 28. Bioorg Med Chem. 2006. PMID: 17010618

10

Structure-guided peptidomimetic design leads to nanomolar beta-hairpin inhibitors of the Tat-TAR interaction of bovine immunodeficiency virus.

Athanassiou Z, Patora K, Dias RL, Moehle K, Robinson JA, Varani G. Athanassiou Z, et al. Among authors: moehle k. Biochemistry. 2007 Jan 23;46(3):741-51. doi: 10.1021/bi0619371. Biochemistry. 2007. PMID: 17223695

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