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Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.
European Network of National Networks studying Gene-Environment Interactions in Schizophrenia (EU-GEI); van Os J, Rutten BP, Myin-Germeys I, Delespaul P, Viechtbauer W, van Zelst C, Bruggeman R, Reininghaus U, Morgan C, Murray RM, Di Forti M, McGuire P, Valmaggia LR, Kempton MJ, Gayer-Anderson C, Hubbard K, Beards S, Stilo SA, Onyejiaka A, Bourque F, Modinos G, Tognin S, Calem M, O'Donovan MC, Owen MJ, Holmans P, Williams N, Craddock N, Richards A, Humphreys I, Meyer-Lindenberg A, Leweke FM, Tost H, Akdeniz C, Rohleder C, Bumb JM, Schwarz E, Alptekin K, Üçok A, Saka MC, Atbaşoğlu EC, Gülöksüz S, Gumus-Akay G, Cihan B, Karadağ H, Soygür H, Cankurtaran EŞ, Ulusoy S, Akdede B, Binbay T, Ayer A, Noyan H, Karadayı G, Akturan E, Ulaş H, Arango C, Parellada M, Bernardo M, Sanjuán J, Bobes J, Arrojo M, Santos JL, Cuadrado P, Rodríguez Solano JJ, Carracedo A, García Bernardo E, Roldán L, López G, Cabrera B, Cruz S, Díaz Mesa EM, Pouso M, Jiménez E, Sánchez T, Rapado M, González E, Martínez C, Sánchez E, Olmeda MS, de Haan L, Velthorst E, van der Gaag M, Selten JP, van Dam D, van der Ven E, van der Meer F, Messchaert E, Kraan T, Burger N, Leboyer M, Szoke A, Schürhoff F, Llorca PM, J… See abstract for full author list ➔ European Network of National Networks studying Gene-Environment Interactions in Schizophrenia (EU-GEI), et al. Among authors: modinos g. Schizophr Bull. 2014 Jul;40(4):729-36. doi: 10.1093/schbul/sbu069. Epub 2014 May 24. Schizophr Bull. 2014. PMID: 24860087 Free PMC article. Review.
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.
Merritt K, McCutcheon RA, Aleman A, Ashley S, Beck K, Block W, Bloemen OJN, Borgan F, Boules C, Bustillo JR, Capizzano AA, Coughlin JM, David A, de la Fuente-Sandoval C, Demjaha A, Dempster K, Do KQ, Du F, Falkai P, Galińska-Skok B, Gallinat J, Gasparovic C, Ginestet CE, Goto N, Graff-Guerrero A, Ho BC, Howes O, Jauhar S, Jeon P, Kato T, Kaufmann CA, Kegeles LS, Keshavan MS, Kim SY, King B, Kunugi H, Lauriello J, León-Ortiz P, Liemburg E, Mcilwain ME, Modinos G, Mouchlianitis E, Nakamura J, Nenadic I, Öngür D, Ota M, Palaniyappan L, Pantelis C, Patel T, Plitman E, Posporelis S, Purdon SE, Reichenbach JR, Renshaw PF, Reyes-Madrigal F, Russell BR, Sawa A, Schaefer M, Shungu DC, Smesny S, Stanley JA, Stone J, Szulc A, Taylor R, Thakkar KN, Théberge J, Tibbo PG, van Amelsvoort T, Walecki J, Williamson PC, Wood SJ, Xin L, Yamasue H, McGuire P, Egerton A; 1H-MRS in Schizophrenia Investigators. Merritt K, et al. Among authors: modinos g. Mol Psychiatry. 2023 May;28(5):2039-2048. doi: 10.1038/s41380-023-01991-7. Epub 2023 Feb 17. Mol Psychiatry. 2023. PMID: 36806762 Free PMC article.
Childhood trauma moderates schizotypy-related brain morphology: analyses of 1182 healthy individuals from the ENIGMA schizotypy working group.
Quidé Y, Watkeys OJ, Tonini E, Grotegerd D, Dannlowski U, Nenadić I, Kircher T, Krug A, Hahn T, Meinert S, Goltermann J, Gruber M, Stein F, Brosch K, Wroblewski A, Thomas-Odenthal F, Usemann P, Straube B, Alexander N, Leehr EJ, Bauer J, Winter NR, Fisch L, Dohm K, Rössler W, Smigielski L, DeRosse P, Moyett A, Houenou J, Leboyer M, Gilleen J, Thomopoulos SI, Thompson PM, Aleman A, Modinos G, Green MJ. Quidé Y, et al. Among authors: modinos g. Psychol Med. 2024 Apr;54(6):1215-1227. doi: 10.1017/S0033291723003045. Epub 2023 Oct 20. Psychol Med. 2024. PMID: 37859592
The prodromal phase of psychosis.
Modinos G, McGuire P. Modinos G, et al. Curr Opin Neurobiol. 2015 Feb;30:100-5. doi: 10.1016/j.conb.2014.11.003. Epub 2014 Nov 28. Curr Opin Neurobiol. 2015. PMID: 25464375 Review.
Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort.
Allen P, Azis M, Modinos G, Bossong MG, Bonoldi I, Samson C, Quinn B, Kempton MJ, Howes OD, Stone JM, Calem M, Perez J, Bhattacharayya S, Broome MR, Grace AA, Zelaya F, McGuire P. Allen P, et al. Among authors: modinos g. Schizophr Bull. 2018 Oct 17;44(6):1323-1331. doi: 10.1093/schbul/sbx169. Schizophr Bull. 2018. PMID: 29294102 Free PMC article.
Gender differences of patients at-risk for psychosis regarding symptomatology, drug use, comorbidity and functioning - Results from the EU-GEI study.
Menghini-Müller S, Studerus E, Ittig S, Heitz U, Egloff L, Andreou C, Valmaggia LR, Kempton MJ, van der Gaag M, de Haan L, Nelson B, Barrantes-Vidal N, Nordentoft M, Ruhrmann S, Sachs G, Rutten BP, Os JV, Riecher-Rössler A; EU-GEI High Risk Study Group; McGuire P, Valmaggia LR, Kempton MJ, Calem M, Tognin S, Modinos G, de Haan L, van der Gaag M, Velthorst E, Kraan TC, van Dam DS, Burger N, Nelson B, McGorry P, Amminger GP, Pantelis C, Politis A, Goodall J, Riecher-Rössler A, Borgwardt S, Rapp C, Ittig S, Studerus E, Smieskova R, Bressan R, Gadelha A, Brietzke E, Asevedo G, Asevedo E, Zugman A, Barrantes-Vidal N, Domínguez-Martínez T, Racioppi A, Cristóbal-Narváez P, Kwapil TR, Monsonet M, Kazes M, Daban C, Bourgin J, Gay O, Mam-Lam-Fook C, Krebs MO, Nordholm D, Randers L, Krakauer K, Glenthøj L, Glenthøj B, Nordentoft M, Ruhrmann S, Gebhard D, Arnhold J, Klosterkötter J, Sachs G, Lasser I, Winklbaur B, Delespaul PA, Rutten BP, van Os J. Menghini-Müller S, et al. Among authors: modinos g. Eur Psychiatry. 2019 Jun;59:52-59. doi: 10.1016/j.eurpsy.2019.04.007. Epub 2019 May 7. Eur Psychiatry. 2019. PMID: 31075522
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