Mochly-Rosen D - Search Results

1

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.

Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knight WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW 2nd. Rocha AG, et al. Science. 2018 Apr 20;360(6386):336-341. doi: 10.1126/science.aao1785. Science. 2018. PMID: 29674596 Free PMC article.

2

Localization of protein kinases by anchoring proteins: a theme in signal transduction.

Mochly-Rosen D. Mochly-Rosen D. Science. 1995 Apr 14;268(5208):247-51. doi: 10.1126/science.7716516. Science. 1995. PMID: 7716516 Review.

3

Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation.

Mochly-Rosen D, Wu G, Hahn H, Osinska H, Liron T, Lorenz JN, Yatani A, Robbins J, Dorn GW 2nd. Mochly-Rosen D, et al. Circ Res. 2000 Jun 9;86(11):1173-9. doi: 10.1161/01.res.86.11.1173. Circ Res. 2000. PMID: 10850970

4

Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC.

Chen L, Hahn H, Wu G, Chen CH, Liron T, Schechtman D, Cavallaro G, Banci L, Guo Y, Bolli R, Dorn GW 2nd, Mochly-Rosen D. Chen L, et al. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11114-9. doi: 10.1073/pnas.191369098. Epub 2001 Sep 11. Proc Natl Acad Sci U S A. 2001. PMID: 11553773 Free PMC article.

5

Intracellular transport mechanisms of signal transducers.

Dorn GW 2nd, Mochly-Rosen D. Dorn GW 2nd, et al. Annu Rev Physiol. 2002;64:407-29. doi: 10.1146/annurev.physiol.64.081501.155903. Annu Rev Physiol. 2002. PMID: 11826274 Review.

6

Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator.

Inagaki K, Hahn HS, Dorn GW 2nd, Mochly-Rosen D. Inagaki K, et al. Circulation. 2003 Aug 19;108(7):869-75. doi: 10.1161/01.CIR.0000081943.93653.73. Epub 2003 Jul 14. Circulation. 2003. PMID: 12860903

7

Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.

Chen CH, Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D. Chen CH, et al. Science. 2008 Sep 12;321(5895):1493-5. doi: 10.1126/science.1158554. Science. 2008. PMID: 18787169 Free PMC article.

8

Correcting mitochondrial fusion by manipulating mitofusin conformations.

Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II. Franco A, et al. Nature. 2016 Dec 1;540(7631):74-79. doi: 10.1038/nature20156. Epub 2016 Oct 24. Nature. 2016. PMID: 27775718 Free PMC article.

9

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW 2nd, Mochly-Rosen D. Joshi AU, et al. Nat Neurosci. 2019 Oct;22(10):1635-1648. doi: 10.1038/s41593-019-0486-0. Epub 2019 Sep 23. Nat Neurosci. 2019. PMID: 31551592 Free PMC article.

10

Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop.

Tian R, Colucci WS, Arany Z, Bachschmid MM, Ballinger SW, Boudina S, Bruce JE, Busija DW, Dikalov S, Dorn GW II, Galis ZS, Gottlieb RA, Kelly DP, Kitsis RN, Kohr MJ, Levy D, Lewandowski ED, McClung JM, Mochly-Rosen D, O'Brien KD, O'Rourke B, Park JY, Ping P, Sack MN, Sheu SS, Shi Y, Shiva S, Wallace DC, Weiss RG, Vernon HJ, Wong R, Schwartz Longacre L. Tian R, et al. Circulation. 2019 Oct 1;140(14):1205-1216. doi: 10.1161/CIRCULATIONAHA.119.040551. Circulation. 2019. PMID: 31769940 Free PMC article. Review.

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