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Co-operative additive effects between HLA alleles in control of HIV-1.
Matthews PC, Listgarten J, Carlson JM, Payne R, Huang KH, Frater J, Goedhals D, Steyn D, van Vuuren C, Paioni P, Jooste P, Ogwu A, Shapiro R, Mncube Z, Ndung'u T, Walker BD, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: mncube z. PLoS One. 2012;7(10):e47799. doi: 10.1371/journal.pone.0047799. Epub 2012 Oct 19. PLoS One. 2012. PMID: 23094091 Free PMC article.
Lack of association between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 subtype C Gag-protease from chronically infected individuals.
Wright JK, Brumme ZL, Julg B, van der Stok M, Mncube Z, Gao X, Carlson JM, Goulder PJ, Walker BD, Brockman MA, Ndung'u T. Wright JK, et al. Among authors: mncube z. J Virol. 2012 Jan;86(2):1273-6. doi: 10.1128/JVI.06533-11. Epub 2011 Nov 16. J Virol. 2012. PMID: 22090116 Free PMC article.
CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles.
Koofhethile CK, Ndhlovu ZM, Thobakgale-Tshabalala C, Prado JG, Ismail N, Mncube Z, Mkhize L, van der Stok M, Yende N, Walker BD, Goulder PJR, Ndung'u T. Koofhethile CK, et al. Among authors: mncube z. J Virol. 2016 Jul 11;90(15):6818-6831. doi: 10.1128/JVI.00276-16. Print 2016 Aug 1. J Virol. 2016. PMID: 27194762 Free PMC article.
Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters.
Wright JK, Brumme ZL, Carlson JM, Heckerman D, Kadie CM, Brumme CJ, Wang B, Losina E, Miura T, Chonco F, van der Stok M, Mncube Z, Bishop K, Goulder PJ, Walker BD, Brockman MA, Ndung'u T. Wright JK, et al. Among authors: mncube z. J Virol. 2010 Oct;84(20):10820-31. doi: 10.1128/JVI.01084-10. Epub 2010 Aug 11. J Virol. 2010. PMID: 20702636 Free PMC article.
High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection.
Gounder K, Padayachi N, Mann JK, Radebe M, Mokgoro M, van der Stok M, Mkhize L, Mncube Z, Jaggernath M, Reddy T, Walker BD, Ndung'u T. Gounder K, et al. Among authors: mncube z. PLoS One. 2015 Mar 17;10(3):e0119886. doi: 10.1371/journal.pone.0119886. eCollection 2015. PLoS One. 2015. PMID: 25781986 Free PMC article.
HIV-1 evades a Gag mutation that abrogates killer cell immunoglobulin-like receptor binding and disinhibits natural killer cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype.
Ziegler MC, Naidoo K, Chapel A, Nkotwana S, Mann J, Mncube Z, Ismael N, Goulder P, Ndung'u T, Altfeld M, Thobakgale CF. Ziegler MC, et al. Among authors: mncube z. AIDS. 2021 Jan 1;35(1):151-154. doi: 10.1097/QAD.0000000000002721. AIDS. 2021. PMID: 33273184 Free PMC article.
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
Crawford H, Prado JG, Leslie A, Hué S, Honeyborne I, Reddy S, van der Stok M, Mncube Z, Brander C, Rousseau C, Mullins JI, Kaslow R, Goepfert P, Allen S, Hunter E, Mulenga J, Kiepiela P, Walker BD, Goulder PJ. Crawford H, et al. Among authors: mncube z. J Virol. 2007 Aug;81(15):8346-51. doi: 10.1128/JVI.00465-07. Epub 2007 May 16. J Virol. 2007. PMID: 17507468 Free PMC article.
Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.
Thobakgale CF, Prendergast A, Crawford H, Mkhwanazi N, Ramduth D, Reddy S, Molina C, Mncube Z, Leslie A, Prado J, Chonco F, Mphatshwe W, Tudor-Williams G, Jeena P, Blanckenberg N, Dong K, Kiepiela P, Coovadia H, Ndung'u T, Walker BD, Goulder PJ. Thobakgale CF, et al. Among authors: mncube z. J Virol. 2009 Oct;83(19):10234-44. doi: 10.1128/JVI.00921-09. Epub 2009 Jul 15. J Virol. 2009. PMID: 19605475 Free PMC article.
24 results