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Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
von Roemeling CA, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, Yang Z, Yang M, Deng W, Bruno KA, Chan CK, Lee AS, Rosenfeld SS, Yun K, Johnson AJ, Mitchell DA, Jiang W, Kim BYS. von Roemeling CA, et al. Among authors: mitchell da. Nat Commun. 2020 Mar 20;11(1):1508. doi: 10.1038/s41467-020-15129-8. Nat Commun. 2020. PMID: 32198351 Free PMC article.
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients.
Mitchell DA, Batich KA, Gunn MD, Huang MN, Sanchez-Perez L, Nair SK, Congdon KL, Reap EA, Archer GE, Desjardins A, Friedman AH, Friedman HS, Herndon JE 2nd, Coan A, McLendon RE, Reardon DA, Vredenburgh JJ, Bigner DD, Sampson JH. Mitchell DA, et al. Nature. 2015 Mar 19;519(7543):366-9. doi: 10.1038/nature14320. Epub 2015 Mar 11. Nature. 2015. PMID: 25762141 Free PMC article. Clinical Trial.
Quantitative characterization of 3D bioprinted structural elements under cell generated forces.
Morley CD, Ellison ST, Bhattacharjee T, O'Bryan CS, Zhang Y, Smith KF, Kabb CP, Sebastian M, Moore GL, Schulze KD, Niemi S, Sawyer WG, Tran DD, Mitchell DA, Sumerlin BS, Flores CT, Angelini TE. Morley CD, et al. Among authors: mitchell da. Nat Commun. 2019 Jul 10;10(1):3029. doi: 10.1038/s41467-019-10919-1. Nat Commun. 2019. PMID: 31292444 Free PMC article.
CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors.
Jin L, Tao H, Karachi A, Long Y, Hou AY, Na M, Dyson KA, Grippin AJ, Deleyrolle LP, Zhang W, Rajon DA, Wang QJ, Yang JC, Kresak JL, Sayour EJ, Rahman M, Bova FJ, Lin Z, Mitchell DA, Huang J. Jin L, et al. Among authors: mitchell da. Nat Commun. 2019 Sep 5;10(1):4016. doi: 10.1038/s41467-019-11869-4. Nat Commun. 2019. PMID: 31488817 Free PMC article.
Oral IRAK-4 Inhibitor CA-4948 Is Blood-Brain Barrier Penetrant and Has Single-Agent Activity against CNS Lymphoma and Melanoma Brain Metastases.
Von Roemeling CA, Doonan BP, Klippel K, Schultz D, Hoang-Minh L, Trivedi V, Li C, Russell RA, Kanumuri RS, Sharma A, Tun HW, Mitchell DA. Von Roemeling CA, et al. Among authors: mitchell da. Clin Cancer Res. 2023 May 1;29(9):1751-1762. doi: 10.1158/1078-0432.CCR-22-1682. Clin Cancer Res. 2023. PMID: 36749885 Free PMC article.
CXCL9 recombinant adeno-associated virus (AAV) virotherapy sensitizes glioblastoma (GBM) to anti-PD-1 immune checkpoint blockade.
von Roemeling C, Yegorov O, Yang C, Klippel K, Russell R, Trivedi V, Bhatia A, Doonan B, Carpenter S, Ryu D, Grippen A, Futch H, Ran Y, Hoang-Minh L, Weidert F, Golde T, Mitchell D. von Roemeling C, et al. Res Sq [Preprint]. 2023 Nov 14:rs.3.rs-3463730. doi: 10.21203/rs.3.rs-3463730/v1. Res Sq. 2023. PMID: 38014191 Free PMC article. Preprint.
587 results