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Page 1
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.
Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. Wang Z, et al. Among authors: mirsoian a. Nat Med. 2019 Jan;25(1):141-151. doi: 10.1038/s41591-018-0221-5. Epub 2018 Nov 12. Nat Med. 2019. PMID: 30420753 Free PMC article.
Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help.
Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ. Monjazeb AM, et al. Among authors: mirsoian a. PLoS One. 2014 Aug 13;9(8):e102709. doi: 10.1371/journal.pone.0102709. eCollection 2014. PLoS One. 2014. PMID: 25119341 Free PMC article.
Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy.
Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. Bouchlaka MN, et al. Among authors: mirsoian a. J Exp Med. 2013 Oct 21;210(11):2223-37. doi: 10.1084/jem.20131219. Epub 2013 Sep 30. J Exp Med. 2013. PMID: 24081947 Free PMC article.
Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.
Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ. Mirsoian A, et al. J Exp Med. 2014 Nov 17;211(12):2373-83. doi: 10.1084/jem.20140116. Epub 2014 Nov 3. J Exp Med. 2014. PMID: 25366964 Free PMC article.
Obesity and cancer immunotherapy toxicity.
Mirsoian A, Murphy WJ. Mirsoian A, et al. Immunotherapy. 2015;7(4):319-22. doi: 10.2217/imt.15.12. Immunotherapy. 2015. PMID: 25917623 Free PMC article. No abstract available.
Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity.
Sckisel GD, Bouchlaka MN, Monjazeb AM, Crittenden M, Curti BD, Wilkins DE, Alderson KA, Sungur CM, Ames E, Mirsoian A, Reddy A, Alexander W, Soulika A, Blazar BR, Longo DL, Wiltrout RH, Murphy WJ. Sckisel GD, et al. Among authors: mirsoian a. Immunity. 2015 Aug 18;43(2):240-50. doi: 10.1016/j.immuni.2015.06.023. Epub 2015 Jul 28. Immunity. 2015. PMID: 26231116 Free PMC article.
Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies.
Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ. Monjazeb AM, et al. Among authors: mirsoian a. Clin Cancer Res. 2016 Sep 1;22(17):4328-40. doi: 10.1158/1078-0432.CCR-15-3026. Epub 2016 Mar 15. Clin Cancer Res. 2016. PMID: 26979392 Free PMC article.
Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer.
Mall C, Sckisel GD, Proia DA, Mirsoian A, Grossenbacher SK, Pai CS, Chen M, Monjazeb AM, Kelly K, Blazar BR, Murphy WJ. Mall C, et al. Among authors: mirsoian a. Oncoimmunology. 2015 Aug 12;5(2):e1075114. doi: 10.1080/2162402X.2015.1075114. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057446 Free PMC article.
16 results