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GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis.
Cordova RA, Misra J, Amin PH, Klunk AJ, Damayanti NP, Carlson KR, Elmendorf AJ, Kim HG, Mirek ET, Elzey BD, Miller MJ, Dong XC, Cheng L, Anthony TG, Pili R, Wek RC, Staschke KA. Cordova RA, et al. Among authors: mirek et. Elife. 2022 Sep 15;11:e81083. doi: 10.7554/eLife.81083. Elife. 2022. PMID: 36107759 Free PMC article.
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Wilson GJ, Lennox BA, She P, Mirek ET, Al Baghdadi RJ, Fusakio ME, Dixon JL, Henderson GC, Wek RC, Anthony TG. Wilson GJ, et al. Among authors: mirek et. Am J Physiol Endocrinol Metab. 2015 Feb 15;308(4):E283-93. doi: 10.1152/ajpendo.00361.2014. Epub 2014 Dec 9. Am J Physiol Endocrinol Metab. 2015. PMID: 25491724 Free PMC article.
Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice.
Pettit AP, Jonsson WO, Bargoud AR, Mirek ET, Peelor FF 3rd, Wang Y, Gettys TW, Kimball SR, Miller BF, Hamilton KL, Wek RC, Anthony TG. Pettit AP, et al. Among authors: mirek et. J Nutr. 2017 Jun;147(6):1031-1040. doi: 10.3945/jn.116.246710. Epub 2017 Apr 26. J Nutr. 2017. PMID: 28446632 Free PMC article.
Age modulates liver responses to asparaginase-induced amino acid stress in mice.
Nikonorova IA, Zhu Q, Signore CC, Mirek ET, Jonsson WO, Kong B, Guo GL, Belden WJ, Anthony TG. Nikonorova IA, et al. Among authors: mirek et. J Biol Chem. 2019 Sep 20;294(38):13864-13875. doi: 10.1074/jbc.RA119.009864. Epub 2019 Aug 14. J Biol Chem. 2019. PMID: 31413113 Free PMC article.
21 results