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HDACi vorinostat protects muscle from degeneration after acute rotator cuff injury in mice.
Gil-Melgosa L, Llombart-Blanco R, Extramiana L, Lacave I, Abizanda G, Miranda E, Agirre X, Prósper F, Pineda-Lucena A, Pons-Villanueva J, Pérez-Ruiz A. Gil-Melgosa L, et al. Among authors: miranda e. Bone Joint Res. 2024 Apr 15;13(4):169-183. doi: 10.1302/2046-3758.134.BJR-2023-0292.R1. Bone Joint Res. 2024. PMID: 38618868 Free PMC article.
Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma.
Rabal O, San José-Enériz E, Agirre X, Sánchez-Arias JA, de Miguel I, Ordoñez R, Garate L, Miranda E, Sáez E, Vilas-Zornoza A, Pineda-Lucena A, Estella A, Zhang F, Wu W, Xu M, Prosper F, Oyarzabal J. Rabal O, et al. Among authors: miranda e. J Med Chem. 2021 Mar 25;64(6):3392-3426. doi: 10.1021/acs.jmedchem.0c02255. Epub 2021 Mar 4. J Med Chem. 2021. PMID: 33661013
Identifying Lethal Dependencies with HUGE Predictive Power.
Gimeno M, San José-Enériz E, Rubio A, Garate L, Miranda E, Castilla C, Agirre X, Prosper F, Carazo F. Gimeno M, et al. Among authors: miranda e. Cancers (Basel). 2022 Jul 1;14(13):3251. doi: 10.3390/cancers14133251. Cancers (Basel). 2022. PMID: 35805023 Free PMC article.
Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.
Vilas-Zornoza A, Agirre X, Abizanda G, Moreno C, Segura V, De Martino Rodriguez A, José-Eneriz ES, Miranda E, Martín-Subero JI, Garate L, Blanco-Prieto MJ, García de Jalón JA, Rio P, Rifón J, Cigudosa JC, Martinez-Climent JA, Román-Gómez J, Calasanz MJ, Ribera JM, Prósper F. Vilas-Zornoza A, et al. Among authors: miranda e. Leukemia. 2012 Jul;26(7):1517-26. doi: 10.1038/leu.2012.31. Epub 2012 Feb 6. Leukemia. 2012. PMID: 22307227 Free article.
Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia.
Vilas-Zornoza A, Agirre X, Martín-Palanco V, Martín-Subero JI, San José-Eneriz E, Garate L, Álvarez S, Miranda E, Rodríguez-Otero P, Rifón J, Torres A, Calasanz MJ, Cruz Cigudosa J, Román-Gómez J, Prósper F. Vilas-Zornoza A, et al. Among authors: miranda e. PLoS One. 2011 Feb 28;6(2):e17012. doi: 10.1371/journal.pone.0017012. PLoS One. 2011. PMID: 21386967 Free PMC article.
Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome.
Rodriguez-Madoz JR, San Jose-Eneriz E, Rabal O, Zapata-Linares N, Miranda E, Rodriguez S, Porciuncula A, Vilas-Zornoza A, Garate L, Segura V, Guruceaga E, Agirre X, Oyarzabal J, Prosper F. Rodriguez-Madoz JR, et al. Among authors: miranda e. PLoS One. 2017 Dec 27;12(12):e0190275. doi: 10.1371/journal.pone.0190275. eCollection 2017. PLoS One. 2017. PMID: 29281720 Free PMC article.
Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated.
Martínez-Calle N, Pascual M, Ordoñez R, Enériz ESJ, Kulis M, Miranda E, Guruceaga E, Segura V, Larráyoz MJ, Bellosillo B, Calasanz MJ, Besses C, Rifón J, Martín-Subero JI, Agirre X, Prosper F. Martínez-Calle N, et al. Among authors: miranda e. Haematologica. 2019 Aug;104(8):1572-1579. doi: 10.3324/haematol.2018.204917. Epub 2019 Jan 17. Haematologica. 2019. PMID: 30655376 Free PMC article.
Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.
Segovia C, San José-Enériz E, Munera-Maravilla E, Martínez-Fernández M, Garate L, Miranda E, Vilas-Zornoza A, Lodewijk I, Rubio C, Segrelles C, Valcárcel LV, Rabal O, Casares N, Bernardini A, Suarez-Cabrera C, López-Calderón FF, Fortes P, Casado JA, Dueñas M, Villacampa F, Lasarte JJ, Guerrero-Ramos F, de Velasco G, Oyarzabal J, Castellano D, Agirre X, Prósper F, Paramio JM. Segovia C, et al. Among authors: miranda e. Nat Med. 2019 Jul;25(7):1073-1081. doi: 10.1038/s41591-019-0499-y. Epub 2019 Jul 3. Nat Med. 2019. PMID: 31270502
Landscape and clinical significance of long noncoding RNAs involved in multiple myeloma expressed fusion transcripts.
Amundarain A, Valcárcel LV, Ordoñez R, Garate L, Miranda E, Cendoya X, Carrasco-Leon A, Calasanz MJ, Paiva B, Meydan C, Mason CE, Melnick A, Rodriguez-Otero P, Martín-Subero JI, San Miguel J, Planes FJ, Prósper F, Agirre X. Amundarain A, et al. Among authors: miranda e. Am J Hematol. 2022 Mar 1;97(3):E113-E117. doi: 10.1002/ajh.26450. Epub 2022 Jan 6. Am J Hematol. 2022. PMID: 34961980 Free article. No abstract available.
880 results