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828 results

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Page 1
MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.
Qian Y, Galan-Cobo A, Guijarro I, Dang M, Molkentine D, Poteete A, Zhang F, Wang Q, Wang J, Parra E, Panda A, Fang J, Skoulidis F, Wistuba II, Verma S, Merghoub T, Wolchok JD, Wong KK, DeBerardinis RJ, Minna JD, Vokes NI, Meador CB, Gainor JF, Wang L, Reuben A, Heymach JV. Qian Y, et al. Among authors: minna jd. Cancer Cell. 2023 Jul 10;41(7):1363-1380.e7. doi: 10.1016/j.ccell.2023.05.015. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327788
Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer.
Wang S, Rong R, Yang DM, Fujimoto J, Bishop JA, Yan S, Cai L, Behrens C, Berry LD, Wilhelm C, Aisner D, Sholl L, Johnson BE, Kwiatkowski DJ, Wistuba II, Bunn PA Jr, Minna J, Xiao G, Kris MG, Xie Y. Wang S, et al. J Clin Invest. 2023 Jan 17;133(2):e160330. doi: 10.1172/JCI160330. J Clin Invest. 2023. PMID: 36647832 Free PMC article.
CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance.
Nilsson MB, Yang Y, Heeke S, Patel SA, Poteete A, Udagawa H, Elamin YY, Moran CA, Kashima Y, Arumugam T, Yu X, Ren X, Diao L, Shen L, Wang Q, Zhang M, Robichaux JP, Shi C, Pfeil AN, Tran H, Gibbons DL, Bock J, Wang J, Minna JD, Kobayashi SS, Le X, Heymach JV. Nilsson MB, et al. Among authors: minna jd. Cancer Cell. 2023 Feb 13;41(2):340-355.e6. doi: 10.1016/j.ccell.2023.01.007. Cancer Cell. 2023. PMID: 36787696 Free PMC article.
Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.
Huffman KE, Li LS, Carstens R, Park H, Girard L, Avila K, Wei S, Kollipara R, Timmons B, Sudderth J, Bendris N, Kim J, Villalobos P, Fujimoto J, Schmid S, Deberardinis RJ, Wistuba I, Heymach J, Kittler R, Akbay EA, Posner B, Wang Y, Lam S, Kliewer SA, Mangelsdorf DJ, Minna JD. Huffman KE, et al. Among authors: minna jd. Front Oncol. 2023 Mar 23;13:1025443. doi: 10.3389/fonc.2023.1025443. eCollection 2023. Front Oncol. 2023. PMID: 37035141 Free PMC article.
Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma.
Kwok HH, Li H, Yang J, Deng J, Lee NC, Au TW, Sit AK, Hsin MK, Ma SK, Cheung LW, Girard L, Fujimoto J, Wistuba II, Gao B, Minna JD, Lam DC. Kwok HH, et al. Among authors: minna jd. Cancer Commun (Lond). 2023 Aug;43(8):951-955. doi: 10.1002/cac2.12449. Epub 2023 Jun 4. Cancer Commun (Lond). 2023. PMID: 37272226 Free PMC article. No abstract available.
Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.
Zhu M, Kim J, Deng Q, Ricciuti B, Alessi JV, Eglenen-Polat B, Bender ME, Huang HC, Kowash RR, Cuevas I, Bennett ZT, Gao J, Minna JD, Castrillon DH, Awad MM, Xu L, Akbay EA. Zhu M, et al. Among authors: minna jd. Cancer Cell. 2023 Oct 9;41(10):1731-1748.e8. doi: 10.1016/j.ccell.2023.09.006. Epub 2023 Sep 28. Cancer Cell. 2023. PMID: 37774698
Cellular senescence and lung cancer prognosis.
Asaithamby A, Shay JW, Minna JD. Asaithamby A, et al. Among authors: minna jd. Transl Lung Cancer Res. 2022 Oct;11(10):1982-1987. doi: 10.21037/tlcr-22-678. Transl Lung Cancer Res. 2022. PMID: 36386455 Free PMC article. No abstract available.
Tumor loss-of-function mutations in STK11/LKB1 induce cachexia.
Iyengar P, Gandhi AY, Granados J, Guo T, Gupta A, Yu J, Llano EM, Zhang F, Gao A, Kandathil A, Williams D, Gao B, Girard L, Malladi VS, Shelton JM, Evers BM, Hannan R, Ahn C, Minna JD, Infante RE. Iyengar P, et al. Among authors: minna jd. JCI Insight. 2023 Apr 24;8(8):e165419. doi: 10.1172/jci.insight.165419. JCI Insight. 2023. PMID: 37092555 Free PMC article.
828 results