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413 results

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Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia.
Märkl F, Schultheiß C, Ali M, Chen SS, Zintchenko M, Egli L, Mietz J, Chijioke O, Paschold L, Spajic S, Holtermann A, Dörr J, Stock S, Zingg A, Läubli H, Piseddu I, Anz D, Minden MD, Zhang T, Nerreter T, Hudecek M, Minguet S, Chiorazzi N, Kobold S, Binder M. Märkl F, et al. Among authors: minden md. Nat Commun. 2024 Feb 2;15(1):993. doi: 10.1038/s41467-024-45378-w. Nat Commun. 2024. PMID: 38307904 Free PMC article.
Precise single-cell transcriptomic mapping of normal and leukemic cell states reveals unconventional lineage priming in acute myeloid leukemia.
Zeng AGX, Iacobucci I, Shah S, Mitchell A, Wong G, Bansal S, Gao Q, Kim H, Kennedy JA, Minden MD, Haferlach T, Mullighan CG, Dick JE. Zeng AGX, et al. Among authors: minden md. bioRxiv [Preprint]. 2023 Dec 27:2023.12.26.573390. doi: 10.1101/2023.12.26.573390. bioRxiv. 2023. PMID: 38234771 Free PMC article. Preprint.
Mitochondria inside acute myeloid leukemia cells hydrolyze ATP to resist chemotherapy.
Hagen JT, Montgomery MM, Aruleba RT, Chrest BR, Green TD, Kassai M, Zeczycki TN, Schmidt CA, Bhowmick D, Tan SF, Feith DJ, Chalfant CE, Loughran TP Jr, Liles D, Minden MD, Schimmer AD, Cabot MC, Mclung JM, Fisher-Wellman KH. Hagen JT, et al. Among authors: minden md. bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589110. doi: 10.1101/2024.04.12.589110. bioRxiv. 2024. PMID: 38659944 Free PMC article. Preprint.
Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure.
Su M, Fleischer T, Grosheva I, Horev MB, Olszewska M, Mattioli CC, Barr H, Plotnikov A, Carvalho S, Moskovich Y, Minden MD, Chapal-Ilani N, Wainstein A, Papapetrou EP, Dezorella N, Cheng T, Kaushansky N, Geiger B, Shlush LI. Su M, et al. Among authors: minden md. iScience. 2024 Mar 6;27(4):109443. doi: 10.1016/j.isci.2024.109443. eCollection 2024 Apr 19. iScience. 2024. PMID: 38558935 Free PMC article.
Outcomes and adverse events in older acute lymphoblastic Leukemia patients treated with a pediatric-inspired protocol with Pegylated or native Asparaginase.
Perusini MA, Andrews C, Atenafu EG, Gupta V, Maze D, Schuh AC, Yee KW, Bankar A, Davidson MB, Richard-Carpentier G, Chan SM, Sibai J, Schimmer AD, Minden MD, Sibai H. Perusini MA, et al. Among authors: minden md. Hematology. 2024 Dec;29(1):2329027. doi: 10.1080/16078454.2024.2329027. Epub 2024 Mar 25. Hematology. 2024. PMID: 38526239
Mutations in myeloid transcription factors and activated signaling genes predict chronic myeloid leukemia outcomes.
Perusini MA, Zackova D PhD, Kim T, Pagnano KBB, Pavlovsky C, Jeziskova I, Kvetková A, Jurcek T, Kim JJ, Yoo YS, Yi S, Lee H, Kim KH, Chang M, Capo-Chichi JM, Medeiros J, Arruda A, Minden MD, Zhang Z, Abelson S Dr, Mayer J, Kim DDH. Perusini MA, et al. Among authors: minden md. Blood Adv. 2024 Mar 6:bloodadvances.2023012127. doi: 10.1182/bloodadvances.2023012127. Online ahead of print. Blood Adv. 2024. PMID: 38447114
Asparaginase completion among adults including older patients with acute lymphoblastic leukemia treated with a modified DFCI protocol.
Perusini MA, Andrews C, Eshetu AG, Gupta V, Maze D, Yee KWL, Bankar A, Davidson MB, Richard-Carpentier G, Chan SM, Schimmer AD, Sibai J, Alharbi S, Lucero JA, Linn SM, Minden MD, Schuh AC, Sibai H. Perusini MA, et al. Among authors: minden md. Leukemia. 2024 Apr;38(4):912-913. doi: 10.1038/s41375-024-02201-1. Epub 2024 Mar 2. Leukemia. 2024. PMID: 38431747 No abstract available.
413 results