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A guiding map for inflammation.
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. Netea MG, et al. Among authors: mills khg. Nat Immunol. 2017 Jul 19;18(8):826-831. doi: 10.1038/ni.3790. Nat Immunol. 2017. PMID: 28722720 Free PMC article.
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Masters SL, et al. Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12. Nat Immunol. 2010. PMID: 20835230 Free PMC article.
Therapeutic potential of targeting IL-17.
Jones SA, Sutton CE, Cua D, Mills KH. Jones SA, et al. Nat Immunol. 2012 Nov;13(11):1022-5. doi: 10.1038/ni.2450. Nat Immunol. 2012. PMID: 23080193
Autophagy and inflammatory diseases.
Jones SA, Mills KH, Harris J. Jones SA, et al. Immunol Cell Biol. 2013 Mar;91(3):250-8. doi: 10.1038/icb.2012.82. Epub 2013 Jan 15. Immunol Cell Biol. 2013. PMID: 23318657 Review.
Protective role for caspase-11 during acute experimental murine colitis.
Oficjalska K, Raverdeau M, Aviello G, Wade SC, Hickey A, Sheehan KM, Corr SC, Kay EW, O'Neill LA, Mills KH, Creagh EM. Oficjalska K, et al. J Immunol. 2015 Feb 1;194(3):1252-60. doi: 10.4049/jimmunol.1400501. Epub 2014 Dec 29. J Immunol. 2015. PMID: 25548224 Free PMC article.
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
223 results