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Rapid tissue prototyping with micro-organospheres.
Wang Z, Boretto M, Millen R, Natesh N, Reckzeh ES, Hsu C, Negrete M, Yao H, Quayle W, Heaton BE, Harding AT, Bose S, Driehuis E, Beumer J, Rivera GO, van Ineveld RL, Gex D, DeVilla J, Wang D, Puschhof J, Geurts MH, Yeung A, Hamele C, Smith A, Bankaitis E, Xiang K, Ding S, Nelson D, Delubac D, Rios A, Abi-Hachem R, Jang D, Goldstein BJ, Glass C, Heaton NS, Hsu D, Clevers H, Shen X. Wang Z, et al. Among authors: millen r. Stem Cell Reports. 2022 Sep 13;17(9):1959-1975. doi: 10.1016/j.stemcr.2022.07.016. Epub 2022 Aug 18. Stem Cell Reports. 2022. PMID: 35985334 Free PMC article.
Patient-derived micro-organospheres enable clinical precision oncology.
Ding S, Hsu C, Wang Z, Natesh NR, Millen R, Negrete M, Giroux N, Rivera GO, Dohlman A, Bose S, Rotstein T, Spiller K, Yeung A, Sun Z, Jiang C, Xi R, Wilkin B, Randon PM, Williamson I, Nelson DA, Delubac D, Oh S, Rupprecht G, Isaacs J, Jia J, Chen C, Shen JP, Kopetz S, McCall S, Smith A, Gjorevski N, Walz AC, Antonia S, Marrer-Berger E, Clevers H, Hsu D, Shen X. Ding S, et al. Among authors: millen r. Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. doi: 10.1016/j.stem.2022.04.006. Epub 2022 May 3. Cell Stem Cell. 2022. PMID: 35508177 Free PMC article.
Uncovering the mode of action of engineered T cells in patient cancer organoids.
Dekkers JF, Alieva M, Cleven A, Keramati F, Wezenaar AKL, van Vliet EJ, Puschhof J, Brazda P, Johanna I, Meringa AD, Rebel HG, Buchholz MB, Barrera Román M, Zeeman AL, de Blank S, Fasci D, Geurts MH, Cornel AM, Driehuis E, Millen R, Straetemans T, Nicolasen MJT, Aarts-Riemens T, Ariese HCR, Johnson HR, van Ineveld RL, Karaiskaki F, Kopper O, Bar-Ephraim YE, Kretzschmar K, Eggermont AMM, Nierkens S, Wehrens EJ, Stunnenberg HG, Clevers H, Kuball J, Sebestyen Z, Rios AC. Dekkers JF, et al. Among authors: millen r. Nat Biotechnol. 2023 Jan;41(1):60-69. doi: 10.1038/s41587-022-01397-w. Epub 2022 Jul 25. Nat Biotechnol. 2023. PMID: 35879361 Free PMC article.
MAIT cells regulate NK cell-mediated tumor immunity.
Petley EV, Koay HF, Henderson MA, Sek K, Todd KL, Keam SP, Lai J, House IG, Li J, Zethoven M, Chen AXY, Oliver AJ, Michie J, Freeman AJ, Giuffrida L, Chan JD, Pizzolla A, Mak JYW, McCulloch TR, Souza-Fonseca-Guimaraes F, Kearney CJ, Millen R, Ramsay RG, Huntington ND, McCluskey J, Oliaro J, Fairlie DP, Neeson PJ, Godfrey DI, Beavis PA, Darcy PK. Petley EV, et al. Among authors: millen r. Nat Commun. 2021 Aug 6;12(1):4746. doi: 10.1038/s41467-021-25009-4. Nat Commun. 2021. PMID: 34362900 Free PMC article.
CD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival.
Millen R, Hendry S, Narasimhan V, Abbott R, Croxford M, Gibbs P, Tie J, Wong HL, Jones I, Kosmider S, Byrne D, Zalcberg J, Fox S, Desai J, Visvanathan K, Ramsay RG, Tran B. Millen R, et al. Clin Transl Immunology. 2020 Jul 17;9(7):e1155. doi: 10.1002/cti2.1155. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32953115 Free PMC article.
Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.
Kong JCH, Guerra GR, Millen RM, Roth S, Xu H, Neeson PJ, Darcy PK, Kershaw MH, Sampurno S, Malaterre J, Liu DSH, Pham TD, Narasimhan V, Wang M, Huang YK, Visvanathan K, McCormick J, Lynch AC, Warrier S, Michael M, Desai J, Murray W, Mitchell C, Ngan S, Phillips WA, Heriot AG, Ramsay RG. Kong JCH, et al. JCO Precis Oncol. 2018 Nov;2:1-15. doi: 10.1200/PO.18.00075. JCO Precis Oncol. 2018. PMID: 35135158
Intestinal-specific activatable Myb initiates colon tumorigenesis in mice.
Malaterre J, Pereira L, Putoczki T, Millen R, Paquet-Fifield S, Germann M, Liu J, Cheasley D, Sampurno S, Stacker SA, Achen MG, Ward RL, Waring P, Mantamadiotis T, Ernst M, Ramsay RG. Malaterre J, et al. Among authors: millen r. Oncogene. 2016 May 12;35(19):2475-84. doi: 10.1038/onc.2015.305. Epub 2015 Aug 24. Oncogene. 2016. PMID: 26300002 Free PMC article.
47 results