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Interrogation of Benzomalvin Biosynthesis Using Fungal Artificial Chromosomes with Metabolomic Scoring (FAC-MS): Discovery of a Benzodiazepine Synthase Activity.
Clevenger KD, Ye R, Bok JW, Thomas PM, Islam MN, Miley GP, Robey MT, Chen C, Yang K, Swyers M, Wu E, Gao P, Wu CC, Keller NP, Kelleher NL. Clevenger KD, et al. Among authors: miley gp. Biochemistry. 2018 Jun 12;57(23):3237-3243. doi: 10.1021/acs.biochem.8b00076. Epub 2018 Mar 20. Biochemistry. 2018. PMID: 29533658 Free PMC article.
A scalable platform to identify fungal secondary metabolites and their gene clusters.
Clevenger KD, Bok JW, Ye R, Miley GP, Verdan MH, Velk T, Chen C, Yang K, Robey MT, Gao P, Lamprecht M, Thomas PM, Islam MN, Palmer JM, Wu CC, Keller NP, Kelleher NL. Clevenger KD, et al. Among authors: miley gp. Nat Chem Biol. 2017 Aug;13(8):895-901. doi: 10.1038/nchembio.2408. Epub 2017 Jun 12. Nat Chem Biol. 2017. PMID: 28604695 Free PMC article.
Nondestructive, high-resolution, chemically specific 3D nanostructure characterization using phase-sensitive EUV imaging reflectometry.
Tanksalvala M, Porter CL, Esashi Y, Wang B, Jenkins NW, Zhang Z, Miley GP, Knobloch JL, McBennett B, Horiguchi N, Yazdi S, Zhou J, Jacobs MN, Bevis CS, Karl RM Jr, Johnsen P, Ren D, Waller L, Adams DE, Cousin SL, Liao CT, Miao J, Gerrity M, Kapteyn HC, Murnane MM. Tanksalvala M, et al. Among authors: miley gp. Sci Adv. 2021 Jan 27;7(5):eabd9667. doi: 10.1126/sciadv.abd9667. Print 2021 Jan. Sci Adv. 2021. PMID: 33571123 Free PMC article.
ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria.
Miley GP, Pou S, Winter R, Nilsen A, Li Y, Kelly JX, Stickles AM, Mather MW, Forquer IP, Pershing AM, White K, Shackleford D, Saunders J, Chen G, Ting LM, Kim K, Zakharov LN, Donini C, Burrows JN, Vaidya AB, Charman SA, Riscoe MK. Miley GP, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5555-60. doi: 10.1128/AAC.01183-15. Epub 2015 Jun 29. Antimicrob Agents Chemother. 2015. PMID: 26124159 Free PMC article.
Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy.
Stickles AM, Ting LM, Morrisey JM, Li Y, Mather MW, Meermeier E, Pershing AM, Forquer IP, Miley GP, Pou S, Winter RW, Hinrichs DJ, Kelly JX, Kim K, Vaidya AB, Riscoe MK, Nilsen A. Stickles AM, et al. Among authors: miley gp. Am J Trop Med Hyg. 2015 Jun;92(6):1195-201. doi: 10.4269/ajtmh.14-0553. Epub 2015 Apr 27. Am J Trop Med Hyg. 2015. PMID: 25918204 Free PMC article.
Discovery, synthesis, and optimization of antimalarial 4(1H)-quinolone-3-diarylethers.
Nilsen A, Miley GP, Forquer IP, Mather MW, Katneni K, Li Y, Pou S, Pershing AM, Stickles AM, Ryan E, Kelly JX, Doggett JS, White KL, Hinrichs DJ, Winter RW, Charman SA, Zakharov LN, Bathurst I, Burrows JN, Vaidya AB, Riscoe MK. Nilsen A, et al. Among authors: miley gp. J Med Chem. 2014 May 8;57(9):3818-34. doi: 10.1021/jm500147k. Epub 2014 Apr 18. J Med Chem. 2014. PMID: 24720377 Free PMC article.
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