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EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.
Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H. Talasila KM, et al. Among authors: miletic h. Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22. Acta Neuropathol. 2013. PMID: 23429996 Free PMC article.
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen PØ, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mørkve SH, Lund-Johansen M, Chalmers AJ, Bjerkvig R, Niclou SP, Gottlieb E. Tardito S, et al. Among authors: miletic h. Nat Cell Biol. 2015 Dec;17(12):1556-68. doi: 10.1038/ncb3272. Epub 2015 Nov 23. Nat Cell Biol. 2015. PMID: 26595383 Free PMC article.
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.
Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Välk K, Al Hossain J, Joseph JV, Jahedi R, Saed HS, Piccirillo SG, Spiteri I, Leiss L, Euskirchen P, Graziani G, Daubon T, Lund-Johansen M, Enger PØ, Winkler F, Ritter CA, Niclou SP, Watts C, Bjerkvig R, Miletic H. Eskilsson E, et al. Among authors: miletic h. Neuro Oncol. 2016 Dec;18(12):1644-1655. doi: 10.1093/neuonc/now113. Epub 2016 Jun 10. Neuro Oncol. 2016. PMID: 27286795 Free PMC article.
Genetic landscape of sporadic vestibular schwannoma.
Håvik AL, Bruland O, Myrseth E, Miletic H, Aarhus M, Knappskog PM, Lund-Johansen M. Håvik AL, et al. Among authors: miletic h. J Neurosurg. 2018 Mar;128(3):911-922. doi: 10.3171/2016.10.JNS161384. Epub 2017 Apr 14. J Neurosurg. 2018. PMID: 28409725
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, Zheng L, Gottlieb E, Niclou SP, Bjerkvig R. Fack F, et al. Among authors: miletic h. Acta Neuropathol. 2015 Jan;129(1):115-31. doi: 10.1007/s00401-014-1352-5. Epub 2014 Oct 17. Acta Neuropathol. 2015. PMID: 25322816 Free PMC article.
Molecular pathogenesis of polymerase γ-related neurodegeneration.
Tzoulis C, Tran GT, Coxhead J, Bertelsen B, Lilleng PK, Balafkan N, Payne B, Miletic H, Chinnery PF, Bindoff LA. Tzoulis C, et al. Among authors: miletic h. Ann Neurol. 2014 Jul;76(1):66-81. doi: 10.1002/ana.24185. Epub 2014 Jun 14. Ann Neurol. 2014. PMID: 24841123 Free PMC article.
Mitochondrial DNA depletion in sporadic inclusion body myositis.
Bhatt PS, Tzoulis C, Balafkan N, Miletic H, Tran GTT, Sanaker PS, Bindoff LA. Bhatt PS, et al. Among authors: miletic h. Neuromuscul Disord. 2019 Mar;29(3):242-246. doi: 10.1016/j.nmd.2019.02.001. Epub 2019 Feb 10. Neuromuscul Disord. 2019. PMID: 30850168 Free article.
123 results