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Blocking glutamate mGlu5 receptors with the negative allosteric modulator CTEP improves disease course in SOD1G93A mouse model of amyotrophic lateral sclerosis.
Milanese M, Bonifacino T, Torazza C, Provenzano F, Kumar M, Ravera S, Zerbo AR, Frumento G, Balbi M, Nguyen TPN, Bertola N, Ferrando S, Viale M, Profumo A, Bonanno G. Milanese M, et al. Br J Pharmacol. 2021 Sep;178(18):3747-3764. doi: 10.1111/bph.15515. Epub 2021 Jun 29. Br J Pharmacol. 2021. PMID: 33931856 Free PMC article.
The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes.
Bonanno G, Raiteri L, Milanese M, Zappettini S, Melloni E, Pedrazzi M, Passalacqua M, Tacchetti C, Usai C, Sparatore B. Bonanno G, et al. Among authors: milanese m. Int Rev Neurobiol. 2007;82:73-93. doi: 10.1016/S0074-7742(07)82004-6. Int Rev Neurobiol. 2007. PMID: 17678956 Review.
262 results