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Page 1
Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
Walker BA, Boyle EM, Wardell CP, Murison A, Begum DB, Dahir NM, Proszek PZ, Johnson DC, Kaiser MF, Melchor L, Aronson LI, Scales M, Pawlyn C, Mirabella F, Jones JR, Brioli A, Mikulasova A, Cairns DA, Gregory WM, Quartilho A, Drayson MT, Russell N, Cook G, Jackson GH, Leleu X, Davies FE, Morgan GJ. Walker BA, et al. Among authors: mikulasova a. J Clin Oncol. 2015 Nov 20;33(33):3911-20. doi: 10.1200/JCO.2014.59.1503. Epub 2015 Aug 17. J Clin Oncol. 2015. PMID: 26282654 Free PMC article. Clinical Trial.
The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma.
Mikulasova A, Wardell CP, Murison A, Boyle EM, Jackson GH, Smetana J, Kufova Z, Pour L, Sandecka V, Almasi M, Vsianska P, Gregora E, Kuglik P, Hajek R, Davies FE, Morgan GJ, Walker BA. Mikulasova A, et al. Haematologica. 2017 Sep;102(9):1617-1625. doi: 10.3324/haematol.2017.163766. Epub 2017 May 26. Haematologica. 2017. PMID: 28550183 Free PMC article.
Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Mikulasova A, Ashby C, Tytarenko RG, Qu P, Rosenthal A, Dent JA, Ryan KR, Bauer MA, Wardell CP, Hoering A, Mavrommatis K, Trotter M, Deshpande S, Yaccoby S, Tian E, Keats J, Auclair D, Jackson GH, Davies FE, Thakurta A, Morgan GJ, Walker BA. Mikulasova A, et al. Haematologica. 2020 Apr;105(4):1055-1066. doi: 10.3324/haematol.2019.217927. Epub 2019 Jun 20. Haematologica. 2020. PMID: 31221783 Free PMC article.
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities.
Oben B, Froyen G, Maclachlan KH, Leongamornlert D, Abascal F, Zheng-Lin B, Yellapantula V, Derkach A, Geerdens E, Diamond BT, Arijs I, Maes B, Vanhees K, Hultcrantz M, Manasanch EE, Kazandjian D, Lesokhin A, Dogan A, Zhang Y, Mikulasova A, Walker B, Morgan G, Campbell PJ, Landgren O, Rummens JL, Bolli N, Maura F. Oben B, et al. Among authors: mikulasova a. Nat Commun. 2021 Mar 25;12(1):1861. doi: 10.1038/s41467-021-22140-0. Nat Commun. 2021. PMID: 33767199 Free PMC article.
Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
Mikulasova A, Kent D, Trevisan-Herraz M, Karataraki N, Fung KTM, Ashby C, Cieslak A, Yaccoby S, van Rhee F, Zangari M, Thanendrarajan S, Schinke C, Morgan GJ, Asnafi V, Spicuglia S, Brackley CA, Corcoran AE, Hambleton S, Walker BA, Rico D, Russell LJ. Mikulasova A, et al. Genome Res. 2022 Jul;32(7):1343-1354. doi: 10.1101/gr.276042.121. Epub 2021 Dec 21. Genome Res. 2022. PMID: 34933939 Free PMC article.
Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Ashby C, Boyle EM, Bauer MA, Mikulasova A, Wardell CP, Williams L, Siegel A, Blaney P, Braunstein M, Kaminetsky D, Keats J, Maura F, Landgren O, Walker BA, Davies FE, Morgan GJ. Ashby C, et al. Among authors: mikulasova a. Blood Cancer J. 2022 May 30;12(5):85. doi: 10.1038/s41408-022-00673-x. Blood Cancer J. 2022. PMID: 35637217 Free PMC article.
Chromosomal abnormalities in multiple myeloma.
Mikulasova A, Morgan GJ, Walker BA. Mikulasova A, et al. Nat Rev Dis Primers. 2022 Jun 16;8(1):42. doi: 10.1038/s41572-022-00374-6. Nat Rev Dis Primers. 2022. PMID: 35710551 No abstract available.
High-resolution simulations of chromatin folding at genomic rearrangements in malignant B cells provide mechanistic insights into proto-oncogene deregulation.
Rico D, Kent D, Karataraki N, Mikulasova A, Berlinguer-Palmini R, Walker BA, Javierre BM, Russell LJ, Brackley CA. Rico D, et al. Among authors: mikulasova a. Genome Res. 2022 Jul 21;32(7):1355-66. doi: 10.1101/gr.276028.121. Online ahead of print. Genome Res. 2022. PMID: 35863900 Free PMC article.
37 results