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Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells.
Białopiotrowicz E, Noyszewska-Kania M, Kachamakova-Trojanowska N, Łoboda A, Cybulska M, Grochowska A, Kopczyński M, Mikula M, Prochorec-Sobieszek M, Firczuk M, Graczyk-Jarzynka A, Zagożdżon R, Ząbek A, Młynarz P, Dulak J, Górniak P, Szydłowski M, Pyziak K, Martyka J, Sroka-Porada A, Jabłońska E, Polak A, Kowalczyk P, Szumera-Ciećkiewicz A, Chapuy B, Rzymski T, Brzózka K, Juszczyński P. Białopiotrowicz E, et al. Among authors: mikula m. Cancers (Basel). 2020 Mar 3;12(3):580. doi: 10.3390/cancers12030580. Cancers (Basel). 2020. PMID: 32138178 Free PMC article.
CDK8 kinase--An emerging target in targeted cancer therapy.
Rzymski T, Mikula M, Wiklik K, Brzózka K. Rzymski T, et al. Among authors: mikula m. Biochim Biophys Acta. 2015 Oct;1854(10 Pt B):1617-29. doi: 10.1016/j.bbapap.2015.05.011. Epub 2015 May 22. Biochim Biophys Acta. 2015. PMID: 26006748 Review.
Prolonged transfer of feces from the lean mice modulates gut microbiota in obese mice.
Kulecka M, Paziewska A, Zeber-Lubecka N, Ambrozkiewicz F, Kopczynski M, Kuklinska U, Pysniak K, Gajewska M, Mikula M, Ostrowski J. Kulecka M, et al. Among authors: mikula m. Nutr Metab (Lond). 2016 Aug 23;13(1):57. doi: 10.1186/s12986-016-0116-8. eCollection 2016. Nutr Metab (Lond). 2016. PMID: 27559357 Free PMC article.
Limited prolonged effects of rifaximin treatment on irritable bowel syndrome-related differences in the fecal microbiome and metabolome.
Zeber-Lubecka N, Kulecka M, Ambrozkiewicz F, Paziewska A, Goryca K, Karczmarski J, Rubel T, Wojtowicz W, Mlynarz P, Marczak L, Tomecki R, Mikula M, Ostrowski J. Zeber-Lubecka N, et al. Among authors: mikula m. Gut Microbes. 2016 Sep 2;7(5):397-413. doi: 10.1080/19490976.2016.1215805. Epub 2016 Jul 26. Gut Microbes. 2016. PMID: 27662586 Free PMC article.
SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains.
Rzymski T, Mikula M, Żyłkiewicz E, Dreas A, Wiklik K, Gołas A, Wójcik K, Masiejczyk M, Wróbel A, Dolata I, Kitlińska A, Statkiewicz M, Kuklinska U, Goryca K, Sapała Ł, Grochowska A, Cabaj A, Szajewska-Skuta M, Gabor-Worwa E, Kucwaj K, Białas A, Radzimierski A, Combik M, Woyciechowski J, Mikulski M, Windak R, Ostrowski J, Brzózka K. Rzymski T, et al. Among authors: mikula m. Oncotarget. 2017 May 16;8(20):33779-33795. doi: 10.18632/oncotarget.16810. Oncotarget. 2017. PMID: 28422713 Free PMC article.
Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts.
Cybulska M, Olesinski T, Goryca K, Paczkowska K, Statkiewicz M, Kopczynski M, Grochowska A, Unrug-Bielawska K, Tyl-Bielicka A, Gajewska M, Mroz A, Dabrowska M, Karczmarski J, Paziewska A, Zając L, Bednarczyk M, Mikula M, Ostrowski J. Cybulska M, et al. Among authors: mikula m. Biomed Res Int. 2018 Dec 19;2018:2954208. doi: 10.1155/2018/2954208. eCollection 2018. Biomed Res Int. 2018. PMID: 30662905 Free PMC article.
Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.
Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M. Szymańska E, et al. Among authors: mikula m. EMBO Mol Med. 2020 Feb 7;12(2):e10812. doi: 10.15252/emmm.201910812. Epub 2020 Jan 13. EMBO Mol Med. 2020. PMID: 31930723 Free PMC article.
Lack of miR-378 attenuates muscular dystrophy in mdx mice.
Podkalicka P, Mucha O, Bronisz-Budzyńska I, Kozakowska M, Pietraszek-Gremplewicz K, Cetnarowska A, Głowniak-Kwitek U, Bukowska-Strakova K, Cieśla M, Kulecka M, Ostrowski J, Mikuła M, Potulska-Chromik A, Kostera-Pruszczyk A, Józkowicz A, Łoboda A, Dulak J. Podkalicka P, et al. Among authors: mikula m. JCI Insight. 2020 Jun 4;5(11):e135576. doi: 10.1172/jci.insight.135576. JCI Insight. 2020. PMID: 32493839 Free PMC article.
SYK inhibition targets acute myeloid leukemia stem cells by blocking their oxidative metabolism.
Polak A, Bialopiotrowicz E, Krzymieniewska B, Wozniak J, Stojak M, Cybulska M, Kaniuga E, Mikula M, Jablonska E, Gorniak P, Noyszewska-Kania M, Szydlowski M, Piechna K, Piwocka K, Bugajski L, Lech-Maranda E, Barankiewicz J, Kolkowska-Lesniak A, Patkowska E, Glodkowska-Mrowka E, Baran N, Juszczynski P. Polak A, et al. Among authors: mikula m. Cell Death Dis. 2020 Nov 6;11(11):956. doi: 10.1038/s41419-020-03156-8. Cell Death Dis. 2020. PMID: 33159047 Free PMC article.
219 results