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Structure and Function in Antimicrobial Piscidins: Histidine Position, Directionality of Membrane Insertion, and pH-Dependent Permeabilization.
Mihailescu M, Sorci M, Seckute J, Silin VI, Hammer J, Perrin BS Jr, Hernandez JI, Smajic N, Shrestha A, Bogardus KA, Greenwood AI, Fu R, Blazyk J, Pastor RW, Nicholson LK, Belfort G, Cotten ML. Mihailescu M, et al. J Am Chem Soc. 2019 Jun 26;141(25):9837-9853. doi: 10.1021/jacs.9b00440. Epub 2019 Jun 13. J Am Chem Soc. 2019. PMID: 31144503 Free PMC article.
The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels.
Comert F, Greenwood A, Maramba J, Acevedo R, Lucas L, Kulasinghe T, Cairns LS, Wen Y, Fu R, Hammer J, Blazyk J, Sukharev S, Cotten ML, Mihailescu M. Comert F, et al. Among authors: mihailescu m. J Biol Chem. 2019 Dec 6;294(49):18557-18570. doi: 10.1074/jbc.RA119.010232. Epub 2019 Oct 16. J Biol Chem. 2019. PMID: 31619519 Free PMC article.
A Potent Host Defense Peptide Triggers DNA Damage and Is Active against Multidrug-Resistant Gram-Negative Pathogens.
Juliano SA, Serafim LF, Duay SS, Heredia Chavez M, Sharma G, Rooney M, Comert F, Pierce S, Radulescu A, Cotten ML, Mihailescu M, May ER, Greenwood AI, Prabhakar R, Angeles-Boza AM. Juliano SA, et al. Among authors: mihailescu m. ACS Infect Dis. 2020 May 8;6(5):1250-1263. doi: 10.1021/acsinfecdis.0c00051. Epub 2020 Apr 17. ACS Infect Dis. 2020. PMID: 32251582 Free PMC article.
Correction to "A Potent Host Defense Peptide Triggers DNA Damage and Is Active against Multidrug-Resistant Gram-Negative Pathogens".
Juliano SA, Serafim LF, Duay SS, Chavez MH, Sharma G, Rooney M, Comert F, Pierce S, Radulescu A, Cotten ML, Mihailescu M, May ER, Greenwood AI, Prabhakar R, Angeles-Boza AM. Juliano SA, et al. Among authors: mihailescu m. ACS Infect Dis. 2020 Sep 11;6(9):2542. doi: 10.1021/acsinfecdis.0c00549. Epub 2020 Aug 19. ACS Infect Dis. 2020. PMID: 32813488 No abstract available.
Pore hydration states of KcsA potassium channels in membranes.
Blasic JR, Worcester DL, Gawrisch K, Gurnev P, Mihailescu M. Blasic JR, et al. Among authors: mihailescu m. J Biol Chem. 2015 Oct 30;290(44):26765-75. doi: 10.1074/jbc.M115.661819. Epub 2015 Sep 14. J Biol Chem. 2015. PMID: 26370089 Free PMC article.
129 results