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Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease.
Miguez A, Gomis C, Vila C, Monguió-Tortajada M, Fernández-García S, Bombau G, Galofré M, García-Bravo M, Sanders P, Fernández-Medina H, Poquet B, Salado-Manzano C, Roura S, Alberch J, Segovia JC, Allen ND, Borràs FE, Canals JM. Miguez A, et al. Cell Mol Life Sci. 2023 Aug 3;80(8):238. doi: 10.1007/s00018-023-04882-w. Cell Mol Life Sci. 2023. PMID: 37535170 Free PMC article.
Human Pluripotent Stem Cell-Derived Neurons Are Functionally Mature In Vitro and Integrate into the Mouse Striatum Following Transplantation.
Comella-Bolla A, Orlandi JG, Miguez A, Straccia M, García-Bravo M, Bombau G, Galofré M, Sanders P, Carrere J, Segovia JC, Blasi J, Allen ND, Alberch J, Soriano J, Canals JM. Comella-Bolla A, et al. Among authors: miguez a. Mol Neurobiol. 2020 Jun;57(6):2766-2798. doi: 10.1007/s12035-020-01907-4. Epub 2020 Apr 30. Mol Neurobiol. 2020. PMID: 32356172 Free PMC article.
CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease.
Comella Bolla A, Valente T, Miguez A, Brito V, Gines S, Solà C, Straccia M, Canals JM. Comella Bolla A, et al. Among authors: miguez a. PLoS One. 2019 Dec 2;14(12):e0224901. doi: 10.1371/journal.pone.0224901. eCollection 2019. PLoS One. 2019. PMID: 31790427 Free PMC article.
Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.
Martín-Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Díaz Barriga G, Edel MJ, Vicario-Abejón C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM. Martín-Ibáñez R, et al. Among authors: miguez a. Development. 2017 Apr 15;144(8):1566-1577. doi: 10.1242/dev.138248. Epub 2017 Mar 13. Development. 2017. PMID: 28289129 Free PMC article.
Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non-cell-autonomous neuronal damage.
Matute-Blanch C, Brito V, Midaglia L, Villar LM, Garcia-Diaz Barriga G, Guzman de la Fuente A, Borrás E, Fernández-García S, Calvo-Barreiro L, Miguez A, Costa-Frossard L, Pinteac R, Sabidó E, Alberch J, Fitzgerald DC, Montalban X, Comabella M. Matute-Blanch C, et al. Among authors: miguez a. Clin Transl Med. 2022 May;12(5):e837. doi: 10.1002/ctm2.837. Clin Transl Med. 2022. PMID: 35538884 Free PMC article. No abstract available.
Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis.
Malhotra S, Fissolo N, Rodríguez-Rivera C, Monreal E, Montpeyo M, Urcelay E, Triviño JC, Pérez-García MJ, Segura MF, Pappolla A, Río J, Vilaseca A, Fernández Velasco JI, Miguez A, Goicoechea C, Martinez-Vicente M, Villar LM, Montalban X, Comabella M. Malhotra S, et al. Among authors: miguez a. Clin Transl Med. 2024 Apr;14(4):e1654. doi: 10.1002/ctm2.1654. Clin Transl Med. 2024. PMID: 38591764 Free PMC article. No abstract available.
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