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NAD precursors cycle between host tissues and the gut microbiome.
Chellappa K, McReynolds MR, Lu W, Zeng X, Makarov M, Hayat F, Mukherjee S, Bhat YR, Lingala SR, Shima RT, Descamps HC, Cox T, Ji L, Jankowski C, Chu Q, Davidson SM, Thaiss CA, Migaud ME, Rabinowitz JD, Baur JA. Chellappa K, et al. Among authors: migaud me. Cell Metab. 2022 Dec 6;34(12):1947-1959.e5. doi: 10.1016/j.cmet.2022.11.004. Cell Metab. 2022. PMID: 36476934 Free PMC article.
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Among authors: migaud me. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Defining NAD(P)(H) Catabolism.
Dhuguru J, Dellinger RW, Migaud ME. Dhuguru J, et al. Among authors: migaud me. Nutrients. 2023 Jul 7;15(13):3064. doi: 10.3390/nu15133064. Nutrients. 2023. PMID: 37447389 Free PMC article. Review.
Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells.
Kropotov A, Kulikova V, Solovjeva L, Yakimov A, Nerinovski K, Svetlova M, Sudnitsyna J, Plusnina A, Antipova M, Khodorkovskiy M, Migaud ME, Gambaryan S, Ziegler M, Nikiforov A. Kropotov A, et al. Among authors: migaud me. J Biol Chem. 2022 Dec;298(12):102615. doi: 10.1016/j.jbc.2022.102615. Epub 2022 Oct 18. J Biol Chem. 2022. PMID: 36265580 Free PMC article.
79 results