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Combination of p38 MAPK inhibitor with PD-L1 antibody effectively prolongs survivals of temozolomide-resistant glioma-bearing mice via reduction of infiltrating glioma-associated macrophages and PD-L1 expression on resident glioma-associated microglia.
Dang W, Xiao J, Ma Q, Miao J, Cao M, Chen L, Shi Y, Yao X, Yu S, Liu X, Cui Y, Zhang X, Bian X. Dang W, et al. Brain Tumor Pathol. 2021 Jul;38(3):189-200. doi: 10.1007/s10014-021-00404-3. Epub 2021 Jul 6. Brain Tumor Pathol. 2021. PMID: 34231121
EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma.
Gai QJ, Fu Z, He J, Mao M, Yao XX, Qin Y, Lan X, Zhang L, Miao JY, Wang YX, Zhu J, Yang FC, Lu HM, Yan ZX, Chen FL, Shi Y, Ping YF, Cui YH, Zhang X, Liu X, Yao XH, Lv SQ, Bian XW, Wang Y. Gai QJ, et al. Among authors: miao jy. Signal Transduct Target Ther. 2022 Feb 2;7(1):33. doi: 10.1038/s41392-021-00855-2. Signal Transduct Target Ther. 2022. PMID: 35105853 Free PMC article.
Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas.
Wang YX, Wu H, Ren Y, Lv S, Ji C, Xiang D, Zhang M, Lu H, Fu W, Liu Q, Yan Z, Ma Q, Miao J, Cai R, Lan X, Wu B, Wang W, Liu Y, Wang DZ, Cao M, He Z, Shi Y, Ping Y, Yao X, Zhang X, Zhang P, Wang JM, Wang Y, Cui Y, Bian XW. Wang YX, et al. Signal Transduct Target Ther. 2022 Mar 11;7(1):72. doi: 10.1038/s41392-022-00890-7. Signal Transduct Target Ther. 2022. PMID: 35273141 Free PMC article.
A map of the spatial distribution and tumour-associated macrophage states in glioblastoma and grade 4 IDH-mutant astrocytoma.
Yin W, Ping YF, Li F, Lv SQ, Zhang XN, Li XG, Guo Y, Liu Q, Li TR, Yang LQ, Yang KD, Liu YQ, Luo CH, Luo T, Wang WY, Mao M, Luo M, He ZC, Cao MF, Chen C, Miao JY, Zeng H, Wang C, Zhou L, Yang Y, Yang X, Wang QH, Feng H, Shi Y, Bian XW. Yin W, et al. Among authors: miao jy. J Pathol. 2022 Oct;258(2):121-135. doi: 10.1002/path.5984. Epub 2022 Jul 25. J Pathol. 2022. PMID: 35723032
161 results