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SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub.
Piazza R, Magistroni V, Redaelli S, Mauri M, Massimino L, Sessa A, Peronaci M, Lalowski M, Soliymani R, Mezzatesta C, Pirola A, Banfi F, Rubio A, Rea D, Stagno F, Usala E, Martino B, Campiotti L, Merli M, Passamonti F, Onida F, Morotti A, Pavesi F, Bregni M, Broccoli V, Baumann M, Gambacorti-Passerini C. Piazza R, et al. Among authors: mezzatesta c. Nat Commun. 2018 Jun 6;9(1):2192. doi: 10.1038/s41467-018-04462-8. Nat Commun. 2018. PMID: 29875417 Free PMC article.
BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene.
Sharma N, Magistroni V, Piazza R, Citterio S, Mezzatesta C, Khandelwal P, Pirola A, Gambacorti-Passerini C. Sharma N, et al. Among authors: mezzatesta c. Mol Cancer. 2015 Jul 16;14:132. doi: 10.1186/s12943-015-0407-0. Mol Cancer. 2015. PMID: 26179066 Free PMC article.
De novo UBE2A mutations are recurrently acquired during chronic myeloid leukemia progression and interfere with myeloid differentiation pathways.
Magistroni V, Mauri M, D'Aliberti D, Mezzatesta C, Crespiatico I, Nava M, Fontana D, Sharma N, Parker W, Schreiber A, Yeung D, Pirola A, Readelli S, Massimino L, Wang P, Khandelwal P, Citterio S, Viltadi M, Bombelli S, Rigolio R, Perego R, Boultwood J, Morotti A, Saglio G, Kim DW, Branford S, Gambacorti-Passerini C, Piazza R. Magistroni V, et al. Among authors: mezzatesta c. Haematologica. 2019 Sep;104(9):1789-1797. doi: 10.3324/haematol.2017.179937. Epub 2019 Feb 28. Haematologica. 2019. PMID: 30819912 Free PMC article.
Age and dPCR can predict relapse in CML patients who discontinued imatinib: the ISAV study.
Mori S, Vagge E, le Coutre P, Abruzzese E, Martino B, Pungolino E, Elena C, Pierri I, Assouline S, D'Emilio A, Gozzini A, Giraldo P, Stagno F, Iurlo A, Luciani M, De Riso G, Redaelli S, Kim DW, Pirola A, Mezzatesta C, Petroccione A, Lodolo D'Oria A, Crivori P, Piazza R, Gambacorti-Passerini C. Mori S, et al. Among authors: mezzatesta c. Am J Hematol. 2015 Oct;90(10):910-4. doi: 10.1002/ajh.24120. Epub 2015 Sep 10. Am J Hematol. 2015. PMID: 26178642 Free article. Clinical Trial.
TNFR2 is required for RIP1-dependent cell death in human leukemia.
Aguadé-Gorgorió J, McComb S, Eckert C, Guinot A, Marovca B, Mezzatesta C, Jenni S, Abduli L, Schrappe M, Dobay MP, Stanulla M, von Stackelberg A, Cario G, Bourquin JP, Bornhauser BC. Aguadé-Gorgorió J, et al. Among authors: mezzatesta c. Blood Adv. 2020 Oct 13;4(19):4823-4833. doi: 10.1182/bloodadvances.2019000796. Blood Adv. 2020. PMID: 33027529 Free PMC article.
Repurposing anthelmintic agents to eradicate resistant leukemia.
Mezzatesta C, Abduli L, Guinot A, Eckert C, Schewe D, Zaliova M, Vinti L, Marovca B, Tsai YC, Jenni S, Aguade-Gorgorio J, von Stackelberg A, Schrappe M, Locatelli F, Stanulla M, Cario G, Bourquin JP, Bornhauser BC. Mezzatesta C, et al. Blood Cancer J. 2020 Jun 26;10(6):72. doi: 10.1038/s41408-020-0339-9. Blood Cancer J. 2020. PMID: 32591499 Free PMC article.
Proteasomes are a target of the anti-tumour drug vinblastine.
Piccinini M, Tazartes O, Mezzatesta C, Ricotti E, Bedino S, Grosso F, Dianzani U, Tovo PA, Mostert M, Musso A, Rinaudo MT. Piccinini M, et al. Among authors: mezzatesta c. Biochem J. 2001 Jun 15;356(Pt 3):835-41. doi: 10.1042/0264-6021:3560835. Biochem J. 2001. PMID: 11389692 Free PMC article.
13 results