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Challenges in Permeability Assessment for Oral Drug Product Development.
Koziolek M, Augustijns P, Berger C, Cristofoletti R, Dahlgren D, Keemink J, Matsson P, McCartney F, Metzger M, Mezler M, Niessen J, Polli JE, Vertzoni M, Weitschies W, Dressman J. Koziolek M, et al. Among authors: mezler m. Pharmaceutics. 2023 Sep 28;15(10):2397. doi: 10.3390/pharmaceutics15102397. Pharmaceutics. 2023. PMID: 37896157 Free PMC article. Review.
Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.
Mezler M, Jones RS, Sangaraju D, Goldman DC, Hoffmann M, Heikkinen AT, Mannila J, Chang JH, Foquet L, Pusalkar S, Chothe PP, Scheer N. Mezler M, et al. Drug Metab Dispos. 2023 Oct;51(10):1391-1402. doi: 10.1124/dmd.123.001398. Epub 2023 Jul 31. Drug Metab Dispos. 2023. PMID: 37524541
Tau in the brain interstitial fluid is fragmented and seeding-competent.
Barini E, Plotzky G, Mordashova Y, Hoppe J, Rodriguez-Correa E, Julier S, LePrieult F, Mairhofer I, Mezler M, Biesinger S, Cik M, Meinhardt MW, Ercan-Herbst E, Ehrnhoefer DE, Striebinger A, Bodie K, Klein C, Gasparini L, Schlegel K. Barini E, et al. Among authors: mezler m. Neurobiol Aging. 2022 Jan;109:64-77. doi: 10.1016/j.neurobiolaging.2021.09.013. Epub 2021 Sep 17. Neurobiol Aging. 2022. PMID: 34655982 Free article.
Trafficking of JC virus-like particles across the blood-brain barrier.
Ye D, Zimmermann T, Demina V, Sotnikov S, Ried CL, Rahn H, Stapf M, Untucht C, Rohe M, Terstappen GC, Wicke K, Mezler M, Manninga H, Meyer AH. Ye D, et al. Among authors: mezler m. Nanoscale Adv. 2021 Feb 9;3(9):2488-2500. doi: 10.1039/d0na00879f. eCollection 2021 May 4. Nanoscale Adv. 2021. PMID: 36134165 Free PMC article.
34 results