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Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology.
Goralski T, Meyerdirk L, Breton L, Brasseur L, Kurgat K, DeWeerd D, Turner L, Becker K, Adams M, Newhouse D, Henderson MX. Goralski T, et al. Among authors: meyerdirk l. bioRxiv [Preprint]. 2023 May 17:2023.05.17.541144. doi: 10.1101/2023.05.17.541144. bioRxiv. 2023. PMID: 37292685 Free PMC article. Updated. Preprint.
Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity.
Zhang H, D'Agostino C, Tulisiak C, Thorwald MA, Bergkvist L, Lindquist A, Meyerdirk L, Schulz E, Becker K, Steiner JA, Cacciottolo M, Kwatra M, Rey NL, Escobar Galvis ML, Ma J, Sioutas C, Morgan TE, Finch CE, Brundin P. Zhang H, et al. Among authors: meyerdirk l. Heliyon. 2023 Apr 19;9(4):e15622. doi: 10.1016/j.heliyon.2023.e15622. eCollection 2023 Apr. Heliyon. 2023. PMID: 37128335 Free PMC article.
Urinary tract infections trigger synucleinopathy via the innate immune response.
Peelaerts W, Mercado G, George S, Villumsen M, Kasen A, Aguileta M, Linstow C, Sutter AB, Kuhn E, Stetzik L, Sheridan R, Bergkvist L, Meyerdirk L, Lindqvist A, Gavis MLE, Van den Haute C, Hultgren SJ, Baekelandt V, Pospisilik JA, Brudek T, Aznar S, Steiner JA, Henderson MX, Brundin L, Ivanova MI, Hannan TJ, Brundin P. Peelaerts W, et al. Among authors: meyerdirk l. Acta Neuropathol. 2023 May;145(5):541-559. doi: 10.1007/s00401-023-02562-4. Epub 2023 Mar 30. Acta Neuropathol. 2023. PMID: 36991261 Free PMC article.
A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model.
Stetzik L, Mercado G, Smith L, George S, Quansah E, Luda K, Schulz E, Meyerdirk L, Lindquist A, Bergsma A, Jones RG, Brundin L, Henderson MX, Pospisilik JA, Brundin P. Stetzik L, et al. Among authors: meyerdirk l. Front Cell Neurosci. 2022 Sep 15;16:944875. doi: 10.3389/fncel.2022.944875. eCollection 2022. Front Cell Neurosci. 2022. PMID: 36187297 Free PMC article.
T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils.
George S, Tyson T, Rey NL, Sheridan R, Peelaerts W, Becker K, Schulz E, Meyerdirk L, Burmeister AR, von Linstow CU, Steiner JA, Galvis MLE, Ma J, Pospisilik JA, Labrie V, Brundin L, Brundin P. George S, et al. Among authors: meyerdirk l. J Parkinsons Dis. 2021;11(2):585-603. doi: 10.3233/JPD-202351. J Parkinsons Dis. 2021. PMID: 33579871 Free PMC article.
15 results